Sensory nerve - OmicsDI

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Organisms

Mus musculus (343)
Homo sapiens (93)
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Caenorhabditis elegans (11)
Colinus virginianus (8)
Aplysia californica (7)
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Organisms

Mus musculus (156)
Rattus norvegicus (26)
Homo sapiens (19)
Aplysia californica (2)
Nematostella vectensis (2)
Danio rerio (2)
Rattus (1)
Oryctolagus cuniculus (1)
Drosophila melanogaster (1)
Oikopleura dioica (1)

Repository

biostudies-arrayexpress (368)
ENA (247)
geo (199)
pride (23)
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EGA (12)
MetaboLights (5)
BioModels (1)
dbGaP (1)
EVA (1)
iProX (1)
jPOST (1)
PanoramaPublic (1)

Tissue

Brain (5)
Nerve cord (3)
Neuron (3)
Cell culture (3)
Peripheral nerve (2)
Electrically active cell (2)
Peripheral ganglion (1)
Sensory ganglion (1)
Sensory nerve (1)
Peritoneal fluid (1)
Sensory processing neuron (1)
Mechanoreceptor cell (1)
Pain receptor cell (1)
Sciatic nerve (1)
Sensory neuron (1)
Tear (1)
Nerve (1)
Spinal ganglion (1)
Sensory neuron of dorsal root ganglion (1)
Spinal root (1)
Skin (1)
Blood serum (1)
Spinal cord (1)
Dorsal root ganglion (1)

Disease

Colorectal Neoplasms (2)
Peripheral neuropathy (1)
Early-life seizures (1)
Parkinson's disease (1)
Diabetes, diabetic peripheral neuropathy (1)
Diabetes (1)
Not applicable (1)
Neurotoxicity (1)
Cataract (1)
Breast cancer (1)
Diabetes Mellitus (1)
Colorectal cancer (1)
Neuropathic pain (1)
Sensory peripheral neuropathy (1)
Herpes simplex (1)
Transthyretin amyloidosis (1)
Neuroblastoma (1)
Sciatic nerve (1)
Disease free (1)

Technology Type

Mass Spectrometry (23)
Shotgun proteomics (11)
Bottom-up proteomics (7)
Data-independent acquisition (4)
Mass spectrometry (3)
Data-dependent acquisition (3)
Affinity purification coupled with mass spectrometry proteomics (3)
DiaPASEF (2)
Gel-based experiment (2)
ILLUMINA, Illumina MiSeq, Illumina HiSeq 2000 (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 2500 (1)
Illumina MiSeq (1)
NMR spectroscopy (1)
Mass spectrometry assay (1)
Top-down proteomics (1)

Instrument Platform

Illumina HiSeq 2500 (24)
Illumina HiSeq 4000 (10)
Illumina NovaSeq 6000 (9)
Illumina HiSeq 2000 (8)
Orbitrap Fusion Lumos (8)
NextSeq 550 (5)
NextSeq 500 (5)
Orbitrap Fusion (4)
HiSeq X Ten (3)
Illumina MiSeq (3)
Liquid Chromatography MS - positive - reverse phase (3)
Single-Cell Extraction: For enzymatic digestion, pronase (Septomyces argeus, 1 mg/mL) was applied for 25 minutes at room temperature for P0 to P8 datasets. Cells were dissociated and triturated into a single-cell suspension in ACSF supplemented with 1% fetal calf serum (FCS) and DNase (1 µL/10 mL). Trituration was performed using three glass Pasteur pipettes of decreasing diameters. For P30 datasets, enzymatic digestion and cell dissociation were carried out using the Worthington Papain Dissociation System, following the manufacturer’s instructions. Single-Nuclei Extraction: For nuclei isolation, the Hibernate™-E Medium was removed, and 500 µL of chilled 0.1X NP40 Lysis Buffer was added. Tissue was homogenized using a Pellet Pestle (15 strokes) and incubated on ice for 5 minutes. The suspension was pipette-mixed 10 times using a wide-bore pipette tip and incubated for an additional 10 minutes on ice. Following lysis, 500 µL of chilled wash buffer was added, and the mixture was pipette-mixed 5 times using a regular-bore pipette tip. The suspension was filtered through a 30 µm cell strainer into a 50 mL tube to remove debris. The filtered suspension was transferred to a 1.5 mL tube and centrifuged at 950 × g for 10 minutes at 4°C. The supernatant was carefully removed, and the nuclei pellet was retained for downstream analysis. (2)
LTQ Orbitrap Elite (2)
TripleTOF 5600 (2)
Q Exactive (2)
Chromium Next GEM Chip G (1)
10X v3 (1)
Chromium Controller (10X Genomics) (1)
Illumina Genome Analyzier Iix (1)
Qubit 3.0 and Nanodrop Lite (1)
Illumina iSeq 100 (1)
Illumina HiSeq 1000 (1)
AB 5500xl Genetic Analyzer (1)
Illumina CanineHD (1)
LTQ Velos (1)
Exactive Plus (1)
Q-Exactive (1)
Q Exactive Plus (1)
Orbitrap Exploris 480 (1)
Q Exactive HF-X (1)

Publication Date

2026 (55)
2025 (53)
2015 (46)
2014 (44)
2024 (40)
2008 (37)
2013 (35)
2011 (34)
2010 (32)
2023 (31)
2020 (30)
2021 (25)
2016 (25)
2022 (23)
2007 (22)
2012 (21)
2009 (20)
2018 (13)
2019 (12)
2017 (12)
2006 (4)
2005 (3)
2004 (2)

CHEBI ID

CHEBI:16830 (1)
CHEBI:66860 (1)
CHEBI:66855 (1)
CHEBI:18139 (1)
CHEBI:66854 (1)
CHEBI:16016 (1)
CHEBI:33984 (1)
CHEBI:28315 (1)
CHEBI:30813 (1)
CHEBI:66847 (1)
CHEBI:28009 (1)
CHEBI:28260 (1)
CHEBI:18222 (1)
CHEBI:91315 (1)
CHEBI:38083 (1)
CHEBI:64424 (1)
CHEBI:29042 (1)
CHEBI:22599 (1)
CHEBI:33942 (1)
CHEBI:27971 (1)
CHEBI:16024 (1)
CHEBI:64519 (1)
CHEBI:64525 (1)
CHEBI:64526 (1)
CHEBI:64446 (1)
CHEBI:66859 (1)
CHEBI:64504 (1)
CHEBI:64520 (1)
CHEBI:64523 (1)
CHEBI:64433 (1)

Metabolite Name

Malonate (2)
P-Cresol (2)
Chenodeoxycholic acid (2)
Phenylacetic acid (2)
L-Arginine (2)
UMP (2)
D-Mannose (2)
Xanthine (2)
Inosine (2)
Hypoxanthine (2)
2-(2,5-dihydroxy-4-methoxyphenyl)-3,5,6,7-tetrahydroxy-3,4-dihydro-2H-1-benzopyran-4-one; 3-(2,5-dihydroxy-4-methoxyphenyl)-1-(2,3,4,6-tetrahydroxyphenyl)propane-1,2-dione; 3,5,7-trihydroxy-6-methoxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; 3,5,7-trihydroxy-6-methoxy-2-(2,3,4-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; 3,5,7-trihydroxy-6-methoxy-2-(2,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one; (1)
N-acetyl-L-2-aminoadipate(2-); (1)
VI2Fuc-nLc6; (1)
3',5'-Diiodo-L-thyronine 4'-O-sulfate; (1)
TG(22:1(13Z)/19:2n6/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); (1)
TG(15:0/22:2(13Z,16Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); TG(15:0/22:4(7Z,10Z,13Z,16Z)/22:4(7Z,10Z,13Z,16Z)); TG(15:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:2(13Z,16Z)); TG(22:2(13Z,16Z)/15:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); TG(22:4(7Z,10Z,13Z,16Z)/15:0/22:4(7Z,10Z,13Z,16Z)); (1)
TG(14:0/15:0/24:0); TG(14:0/24:0/15:0); TG(15:0/14:0/24:0); TG(15:0/16:0/22:0); TG(15:0/18:0/20:0); (1)
Shoyuflavone C; (1)
4-Hydroxycinnamoylagmatine; (1)
Tipranavir; (1)
N-Acetyltryptophan; Methylphenobarbital; Nigellicine; cyclic 6-Hydroxymelatonin; (1)
Sialyllacto-N-tetraose a; Sialyllacto-N-neotetraose c; Sialyllacto-N-tetraose b; LS tetrasaccharide d; Sialyllacto-N-tetraose c; (1)
Ganglioside GD3 (d18:1/12:0); (1)
L-Tryptophan; D-Tryptophan; 3-Hydroxymethylantipyrine; Ethotoin; (Â±)-Tryptophan; (1)
Vinylacetylglycine; Trimethadione; 5-ethyl-5-methyl-2,4-oxazolidinedione; 6-Oxopiperidine-2-carboxylic acid; (1)
Glutamyltryptophan; Tryptophyl-Glutamate; gamma-Glutamyltryptophan; (1)
Norlaudanosoline; Pipermethystine; noroxymorphone; (1)
Ethyl 2-mercaptopropionate; Methyl 3-mercaptobutanoate; Methyl 3-(methylthio)propanoate; Ethyl 2-(methylthio)acetate; Ethyl 3-mercaptopropanoic acid; (1)
Olmesartan; (1)
De-O-methylsterigmatocystin; Aurantricholide B; {3-[2-(3,5-dihydroxyphenyl)ethyl]phenyl}oxidanesulfonic acid; Dihydroresveratrol 3-sulfate; Dihydroresveratrol 4'-sulfate; (1)

First Public Date

2025 (49)
2026 (46)
2024 (38)
2023 (20)
2020 (20)
2022 (15)
2021 (13)
2014 (12)
2019 (9)
2018 (9)
2017 (9)
2015 (3)
2013 (3)
2016 (1)

Modelling Approach

Ordinary differential equation model (1)

Study status

Completed (4)
Recruiting (2)
Not provided (1)

Lab affiliation

Imperial College, Medicine, Level 3 Sherfield Building, Exhibition Road, SW7 2AZ London (2)
University of Vienna (2)
Physiology & Pharmacology, Cumming School of Medicine, University of calgary, Cagary (1)
Key Laboratory of Neuroregeneration, Nantong University, Nantong, China. (1)
Nerve Regeneration Group, Neurodegeneration Team, IBMC/i3S (1)
Montpellier Hospital (1)
Department of Immunobiology, College of Life Science and Technology, Jinan University, Guangzhou, China. (1)
Population Health Sciences, Virginia Maryland College of Veterinary Medicine, Virginia Polytechnic Institute & State University (1)
The University of Guelph, Guelph, Ontario, Canada. The department of Biomedical Sciences at the Ontario Veterinary College. (1)
Department of Neurobiology, Harvard Medical School; Boston, USA. (1)
Department of Molecular Genetics Faculty of Biochemistry Weizmann Institute of Science Rehovot 7610001 Israel (1)
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Spatial Proteomics Group, Berlin, Germany (lab head) (1)
Department of Brain Sciences, Division of Neuroscience, Imperial College London, London, UK (1)
Primary Investigator, Assistant Professor, Division of Biosciences, College of Dentistry, Ohio State University (1)
Xi'an Central Hospital (1)
Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631 (1)
Tongji University (1)
University of Piemonte Orientale (1)
Target Discovery Institute, NDM Research Building, University of Oxford, Old Road Campus, Oxford, UK (1)
University (1)
TIGEM (1)

Keyword

Leucovorin (2)
Xaliproden hydrochloride (1)
Paresthesia (1)
Neglected Diseases (1)
Orphan Diseases (1)
Rare Disease Research (1)
Registries (1)
Batten Disease (1)
Mucolipidosis IV (1)
Undiagnosed (1)
Uncommon Disease (1)
Hypersomnia (1)
Marinesco-Sjogren Syndrome (1)
4p-/Wolf-Hirschhorn Syndrome (1)
Wiedermann-Steiner Syndrome (1)
Hemophagocytic Lymphohistiocytosis (HLH) (1)
Behcet’s Disease (1)
Jansen metaphyseal chondrodysplasia (1)
Chronic recurrent multifocal osteomyelitis (CRMO) (1)
Hereditary Sensory and Autonomic Neuropathy (1)
Nephropathic infantile cystinosis (1)
Ocular cystinosis (1)
Spinal Bulbar Muscular Atrophy (SBMA) (1)
Mucolipidosis (1)
Mitochondrial aminoacyl-tRNA synthetases (Mt-aaRS Disorders) (1)
Shine Syndrome (1)
Intestinal Bromhidrosis Syndrome (1)
Autosomal recessive extra oral halitosis (1)
CACNA1H mutation (1)
Dimethylglycine dehydrogenase deficiency (1)

IsPrivate

False (1)

Study type

Transcription profiling by array (227)
RNA-seq of coding RNA (79)
RNA-seq of coding RNA from single cells (16)
Unknown experiment type (7)
ChIP-seq (6)
Animal - High-throughput sequencing (4)
Methylation profiling by high throughput sequencing (4)
Interventional (4)
ChIP-chip by tiling array (3)
Transcription profiling by tiling array (3)
Transcription profiling by SAGE (2)
Cell line - Single-cell sequencing (2)
Cell line - High-throughput sequencing (2)
Methylation profiling by array (2)
RNA-seq of non coding RNA (2)
Observational (2)
Differential (1)
Genotyping by array (1)
Transcription profiling by RT-PCR (1)
Spatial transcriptomics by high-throughput sequencing (1)
Comparative genomic hybridization by array (1)
Other (1)
MicroRNA profiling by array (1)
DNA-seq (1)
CUT&RUN (1)
Observational patient registry (1)

Release Date

2025 (332)
2022 (306)
2024 (280)
2021 (277)
2023 (275)
2020 (220)
2019 (184)
2018 (166)
2015 (146)
2017 (143)
2016 (131)
2014 (129)
2013 (98)
2011 (82)
2012 (69)
2026 (66)
2010 (63)
2008 (62)
2009 (56)
2007 (38)
2006 (16)
2004 (13)
2002 (9)
2005 (8)
2003 (8)
2000 (5)
2001 (4)
1999 (3)
1998 (1)
1997 (1)

Location

Australia (4)
Spain (2)
United States (2)
Portugal (1)
Chile (1)
Greece (1)
Russia (1)
Poland (1)
Germany (1)
Argentina (1)
Italy (1)
Belgium (1)
Brazil (1)
Hungary (1)
Canada (1)
United Kingdom (1)

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Rat motor and sensory nerve LC-MSMS

Peripheral nerve repair and functional recovery depend on the rate of nerve regeneration and the quality of target reinnervation. It is important to fully understand the cellular and molecular basis underlying the specificity of peripheral nerve regeneration, which means the achieving of respective ...

ORGANISM(S): Rattus norvegicus (Rat)

2020-12-10 | PXD022097 | Pride

Rat sensory and motor nerve fibroblasts LC-MSMS

In this study, a quantitative proteomic technique based on isobaric tags for relative and absolute quantitation (iTRAQ) was used to compare the proteome of cultured sensory and motor nerve fibroblasts (Fbs). Among a total of 2597 overlapping proteins identified, we obtained 148 differentially expres...

ORGANISM(S): Rattus norvegicus (Rat)

2023-03-11 | PXD034827 | Pride

Lc-msms Sensory nerve fibroblasts Motor nerve fibroblasts Rat

RNA-Seq of DRG and dorsal cord after nerve injury

Genes are up and down regualted in DRG and spinal dorsal cord after peripheral nerve injury WT male adult with sciatic and femoral nerve transection 7 days, RNA was purified from ipilateral or contralateral L4-L6 DRGs or lumbar spinal dorsal cords

ORGANISM(S): Mus musculus

2015-12-10 | E-GEOD-66619 | biostudies-arrayexpress

Comparative proteomics analysis of growth-primed adult dorsal root ganglia reveals key molecular mediators for peripheral nerve regeneration

Peripheral nerve injuries due to physical insults or chronic diseases are quite common, yet no pharmacological therapies are available for the effective repair of injured nerves. The slow growth rate of adult nerves and insufficient access to growth factors pose major hurdles in timely reinnervating...

ORGANISM(S): Rattus norvegicus (Rat)

2023-01-06 | PXD031927 | Pride

Spinal root Rat Comparative proteomics Sciatic nerve Drgs Sensory neuron of dorsal root ganglion Nerve regeneration

Transcription profiling time series of rat retina after intra-orbital nerve transection, intra-orbital nerve crush or no treatment

Array experiment: Animals were divided into a control group (naive), which did not undergo any experimental manipulation (n=20) and two experimental groups, one receiving an intra-orbital nerve transection (IONT, n=60) and the other an intra-orbital nerve crush (IONC, n=60) Sterile precautions were ...

ORGANISM(S): Rattus norvegicus

2008-06-14 | E-MEXP-1387 | biostudies-arrayexpress

Expression data from FACS purified nociceptor neurons from peripheral sensory ganglia

The goal of this study was to analyze global gene expression in specific populations of nociceptor sensory neurons, the neurons that detect damaging/noxious stimuli. The dorsal root ganglia (DRG), trigeminal ganglia, and nodose ganglia are anatomically distinct peripheral sensory ganglia that contai...

ORGANISM(S): Mus musculus

2013-08-28 | E-GEOD-46546 | biostudies-arrayexpress

Transcription profiling of rat Postnatal developmental changes in Sprague-Dawley animals in the model of neuropathic pain - spare nerve injury

Neuropathic pain is an apparently spontaneous experience triggered by abnormal physiology of the peripheral or central nervous system, which evolves with time. Neuropathic pain arising from peripheral nerve injury is characterized by a combination of spontaneous pain, hyperalgesia and allodynia. The...

ORGANISM(S): Rattus norvegicus

2010-01-30 | E-GEOD-15041 | biostudies-arrayexpress

Rac1 inhibition prevents cytoskeleton dysfunction and axonal degeneration in Transthyretin Amyloid Polyneuropathy

Transthyretin Amyloid Polyneuropathy (ATTR-PN) is characterized by the deposition of amyloidogenic TTR particularly in dorsal root ganglia (DRG) and peripheral nerve axons leading to a sensory axonopathy. Here, we investigated the role of cytoskeleton alterations in peripheral axons from an ATTR-PN ...

ORGANISM(S): Mus musculus (Mouse)

2025-10-10 | PXD054291 | Pride

Transthyretin axonopathy transthyretin amyloid polyneuropathy cytoskeleton microtubule dynamics actin axonal transport peripheral nervous system rac1

Sensory nerve-secreted factors regulate basal keratinocyte function in vitro

Injuries to the skin can result in non-healing wounds, characterized by prolonged inflammation, failure to close, and chronic pain. Basal keratinocytes in the epidermis respond to signals activated following injury by proliferating, migrating, and differentiating to restore the epidermal barrier. Th...

ORGANISM(S): Mus musculus (Mouse)

2025-03-28 | PXD062182 | Pride

Wound healing Cell migration Cell proliferation Re-epithelialization Secretome

Derivation of sensory neurons from iPSCs.

Characterization of the gene expression changes accompanying the differentiation of hPSC-sensory from embryonic stem cells through to neuronal precursor cells. We also compare the time course gene expression profile to that of the relevant primary human tissue, human dorsal root ganglia (hDRG). A re...

ORGANISM(S): Homo sapiens

2014-10-22 | E-MTAB-3031 | biostudies-arrayexpress

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