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TranscriptomicsGene expression changes in the septum: possible implications for microRNAs in sculpting the maternal brain.
The transition from the non-maternal to the maternal state is characterized by a variety of CNS alterations that support the care of offspring. The septum (including lateral and medial portions) is a brain region previously linked to various emotional and motivational processes, including maternal c...
ORGANISM(S): Mus musculus 
2012-08-22 | E-GEOD-30836 | biostudies-arrayexpress
ProteomicsNasal septum deviation as the consequence of BMP-controlled changes to cartilage properties
Nasal septum deviation (NSD) is a common abnormality of the septal cartilage often associated with disordered breathing. The etiology of NSD is unknown. BMP7 neural crest-knockout mice, a well-characterized model for midfacial hypoplasia and nasal airway obstruction, develops a deviated septum by 4 ...
ORGANISM(S): Mus musculus (Mouse) 
2021-04-30 | PXD024813 | Pride
Septum Cartilage Bmp 
TranscriptomicsTranscription profiling of models of cardiac remodelling: myocardial infarction or transverse aortic constriction in left ventricle free wall and septum
We employed the Affymetrix GeneChip technology to evaluate the patterns of expression in two different in vivo models of cardiac remodeling and in two different regions (left ventricle free wall and septum) of the heart. Mice underwent transverse aortic constriction (TAC); myocardial infarction (MI)...
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-415 | biostudies-arrayexpress
GenomicsOtx2 controls regional patterning within the MGE and regional identity of the septum [ChIP-Seq]
The Otx2 homeobox transcription factor is essential for gastrulation and early neural development. We generated Otx2 conditional knockout (cKO) mice to investigate its roles in telencephalon development after E9.0. We conducted transcriptional profiling and in situ hybridization to identify genes de...
ORGANISM(S): Mus musculus 
2015-06-10 | E-GEOD-69724 | biostudies-arrayexpress
TranscriptomicsFz1Fz2 double knock out mouse palate microarray (E13.5)
The closure of an open anatomical structure by the directed growth and fusion of two tissue masses is a recurrent theme in mammalian embryology, and this process plays an integral role in the development of the palate, ventricular septum, neural tube, urethra, diaphragm, and eye. In mice, targeted ...
ORGANISM(S): Mus musculus 
2010-09-22 | E-GEOD-24276 | biostudies-arrayexpress
ProteomicsLC-MS/MS analysis of GLUT4-associated proteins in mouse lateral septum tissue after social novelty preference
This dataset contains raw mass spectrometry files from mouse lateral septum samples collected after the social novelty preference test. Lateral septum tissues were incubated with synthetic GLUT4 WT or GLUT4 2A peptides, followed by GLUT4 immunoprecipitation and LC-MS/MS analysis. The experiment was ...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-20 | PXD079796 | Pride
Mouse brain social 
TranscriptomicsEffect of 10 or 25 days cortisol treatment on late gestation fetal septum
We have previously shown in sheep that 10 days of modest chronic increase in maternal cortisol result in fetal heart enlargement and Purkinje cell apoptosis. In subsequent studies in which we extended the duration of cortisol infusion (1mg/kg/d) to term, we found a dramatic incidence of stillbirth i...
ORGANISM(S): Ovis aries 
2014-08-07 | E-GEOD-54237 | biostudies-arrayexpress
GenomicsSpatial transcriptomics of P35 septum
Spatial transcriptomics of P35 septum
PRJNA1187250 | ENA
GenomicsMolecular profiling of lateral septum neurotensin neurons using viralTRAP
Molecular profiling of lateral septum neurotensin neurons using viralTRAP
PRJNA647385 | ENA
TranscriptomicsLarge Scale Expression Changes of Genes Related to Neuronal Signaling and Developmental Processes Found in Lateral Septum of Postpartum Outbred Mice
Coordinated gene expression changes across the CNS help to produce the mammalian maternal phenotype. Lateral septum (LS) is a brain region critically involved with aspects of maternal care, and we recently examined gene expression of whole septum (LS and medial septum) in selectively bred maternal ...
ORGANISM(S): Mus musculus 
2013-03-26 | E-GEOD-43627 | biostudies-arrayexpress
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