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ProteomicsLongitudinal proteomic analysis of influenza HA-reactive IgG antibody repertoire over multiple years and repeated vaccinations
Longitudinal proteomic analysis of H1N1 A/California/7/2009 (CA09) hemagglutinin (HA)-reactive serum IgG antibody repertoire over 5 years and multiple (yearly) vaccinations (both pre- and post-vaccination samples) in a donor. Dataset consists of steady-state (pre-vaccination at day 0) and peak-respo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-11-08 | MSV000083120 | MassIVE
ProteomicsBenchmarking of mass spectrometry-based antibody repertoire profiling reveals extensive systematic biases
The serum antibody repertoire is crucial for long-term immune protection, holding significant immunological and biotechnological value. Bottom-up proteomics is the most widely used mass spectrometry (MS) technique for profiling the sequence diversity of serum antibodies. However, serum antibody bott...
ORGANISM(S): Homo sapiens (Human) 
2025-12-04 | PXD055846 | Pride
Serum antibody bottom-up proteomics (ab-seq) Ms Antibody sequencing Serum antibody repertoire 
ProteomicsProfiling antibody function on antigen arrays
Humoral immune responses are traditionally characterized by determining the presence and quality of antibodies specific for certain antigens. Arraying of large numbers of antigens allows the parallel measurement of antibodies, generating patterns called antibody profiles. Functional characterization...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-12943 | biostudies-arrayexpress
ProteomicsNorovirus serum IgG and IgA repertoire
Dissecting the Clonal Composition and Determinants of Neutralization Potency Enhancement of Circulating Dimeric and Monomeric IgA to Human Norovirus
ORGANISM(S): Homo sapiens (Human) 
2026-07-09 | PXD066704 | Pride
Norovirus Antibody repertoire Igg Iga Serum proteomics 
ProteomicsSerum antibody repertoire to influenza HA
Molecular Features of the Serological IgG Repertoire Elicited by Egg-based, Cell-based, or Recombinant HA Seasonal Influenza Vaccines. __sample information__ Donorname day0S1 or day28S2 Elu or FT Pf number A1 S1 FT 7649_JL_5a.raw A1 S1 FT 7649_JL_5b.raw A1 S1 FT 7649_JL_5c.raw A1 S2 FT 7649_JL_7a.r...
ORGANISM(S): Homo sapiens (Human) 
2025-01-15 | PXD046473 | Pride
Influenza Vaccine Antibody repertoire 
ProteomicsProteomic Analysis of Human Serum Antibody Repertoire Response to Influenza Vaccine
Proteomic profiling of serum antibody repertoire response to FluZone trivalent influenza vaccine in four healthy human subjects. Dataset consists of collected pre-vaccination (Day 0) and post-vaccination (Days 28 and 180) serum IgG samples enriched by affinity chromatography against individual mono...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000080184 | MassIVE
ProteomicsTemplate-based assembly of proteomic short reads for de novo antibody sequencing and repertoire profiling
We developed a software package STITCH (https://github.com/snijderlab/stitch) to perform template-based assembly of de novo peptide reads from antibody samples. As a test case we generated de novo peptide reads from protein G purified whole IgG from COVID-19 patients.
ORGANISM(S): Homo sapiens (Human) 
2022-07-21 | PXD031941 | Pride
De novo  antibody  serum 
UnknownSerum Antibody Repertoire Profiling Using In Silico Antigen Screen.
Not available
S-EPMC3695087 | biostudies-literature
TranscriptomicsAntibody repertoire sequencing of human tonsillar B cell subsets
In response to antigen challenge, human B cells clonally expand, undergo selection and differentiate within secondary lymphoid tissues to produce mature B cell subsets and high affinity antibodies necessary for an effective immune response. However, the interplay between affinity, antibody class and...
ORGANISM(S): Homo sapiens 
2020-05-01 | E-MTAB-8999 | biostudies-arrayexpress
ProteomicsInfluenza vaccination in the elderly boosts antibodies against conserved viral proteins and egg-produced glycans
Proteomic analysis of serum IgG antibody repertoire against influenza vaccine H1 (H1N1 A/California/7/2009) and H3 (H3N2 A/Texas/50/2012) in young, middle-aged, and elderly donors vaccinated with Fluzone 2013-14/14-15. Dataset consists of peak-response (days 21-28 post-vaccination) serum IgG samples...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000086108 | MassIVE
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