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ProteomicsDexamethasone is a regulator of human testicular peritubular cells / Proteome 24 h
The functions of human testicular peritubular cells (HTPCs), which form a small compartment located between the seminiferous epithelium and the interstitials areas of the testis, go beyond intratesticular sperm transport and include immunological roles. The expression of the glucocorticoid receptor ...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD033514 | Pride
Human male fertility  human testis  dexamethasone  cytokines  inflammation  proteomics 
ProteomicsDexamethasone is a regulator of human testicular peritubular cells / Proteome 72 h
The functions of human testicular peritubular cells (HTPCs), which form a small compartment located between the seminiferous epithelium and the interstitials areas of the testis, go beyond intratesticular sperm transport and include immunological roles. The expression of the glucocorticoid receptor ...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD033534 | Pride
Human male fertility  human testis  dexamethasone  cytokines  inflammation  proteomics 
ProteomicsSir4 H-BRCT domain interacts with multiple phospho-proteins to regulate heterochromatic repression
In Saccharomyces cerevisiae, the Silent Information Regulator (SIR) proteins Sir2/3/4 form a complex suppressing transcription of genes at subtelomeric regions and the homothallic mating type (HM) loci. Here we identify a non-canonical BRCA1 C-terminal domain (H-BRCT) in Sir4 which is responsible fo...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-09-13 | PXD014119 | Pride
Tom1 Sir complex Heterochromatin Brct Dbf4 
Transcriptomicspoly(A) specific ribonuclease (PARN)-dependent trimming of H ACA box RNAs
Microarray comprising probe sets for miRNAs and other small RNAs was used to determine which and how many small RNAs are potential substrates of poly(A) specific ribonuclease (PARN) in U2OS cells . Hybridization probes were generated by oligo(dT) priming.
ORGANISM(S): Homo sapiens 
2012-02-17 | E-MEXP-3344 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse islets treated with PANcreatic DERived factor for 48 or 72 h to elucidate the genetic mechanisms of PANDER-induced cell death
Expression profiling using the UPenn Mouse PancChip 5.0 was used to elucidate the genetic mechanisms of PANDER-induced cell death in pancreatic islets. Murine islets were treated with PANDER (PANcreatic DERived factor) for 48 or 72 h (n=4 and n=3 respectively). Following linear amplification, the ...
ORGANISM(S): Mus musculus 
2006-05-24 | E-CBIL-7 | biostudies-arrayexpress
GenomicsBrucella MucR acts as an H-NS-like protein to silence virulence genes and structure the nucleoid 
Histone-like nucleoid structuring (H-NS) and H-NS-like proteins serve as global gene silencers and work with antagonistic transcriptional activators (counter- silencers) to properly coordinate the expression of virulence genes in pathogenic bacteria. In Brucella, MucR has been proposed as a novel H-...
ORGANISM(S): Brucella abortus 2308 
2023-09-16 | GSE234935 | GEO
GenomicsBrucella MucR acts as an H-NS-like protein to silence virulence genes and structure the nucleoid 
Brucella MucR acts as an H-NS-like protein to silence virulence genes and structure the nucleoid 
PRJNA983775 | ENA
TranscriptomicsRice global gene expression profile in response to plant hormones
A time course gene expression profiling of rice treated with various plant hormones (abscisic acid, gibberelin, auxin, brassinosteroid, cytokinin and jasmonic acid) was performed to obtain an overall signature of the rice transcriptome in response to each phytohormone. The transcriptome of rice see...
ORGANISM(S): Oryza sativa Japonica Group 
2012-12-03 | E-GEOD-39429 | biostudies-arrayexpress
ModelsKoenig2012 - Hepatic Glucose Metabolism
Quantifying the Contribution of the Liver to Glucose Homeostasis: A Detailed Kinetic Model of Human Hepatic Glucose Metabolism Kinetic Model of Human Hepatic Glucose Metabolism Authors Matthias Koenig, Sasc...
2005-01-01 | MODEL1204270001 | BioModels
TranscriptomicsGene expression profiling in human fibroblast after low-LET irradiation
Exposure to radiation provokes cellular responses controlled in part by gene expression networks. MicroRNAs (miRNAs) are small non-coding RNAs which mostly regulate gene expression by degrading the messages or inhibiting translation. Here, we investigated changes in miRNA expression patterns after l...
ORGANISM(S): Homo sapiens 
2010-06-20 | E-GEOD-12647 | biostudies-arrayexpress
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