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UnknownNontoxic Targeting of Energy Metabolism in Preclinical VM-M3 Experimental Glioblastoma.
Not available
S-EPMC6186985 | biostudies-literature
ProteomicsRegulation of the Endocytosis and Prion Chaperoning Machineries by Yeast E3 Ubiquitin Ligase Rsp5 as Revealed by Orthogonal Ubiquitin Transfer
Attachment of the ubiquitin (UB) peptide to proteins via the E1-E2-E3 enzymatic machinery regulates diverse biological pathways, yet identification of the substrates of E3 UB ligases remains a challenge. We overcame this challenge by constructing an “orthogonal UB transfer (OUT) cascade with yeast E...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-13 | PXD023688 | Pride
Ubiquitin Lc-ms/ms 
UnknownPsychometric Properties of the WBIS/M in a Representative Prebariatric Sample: Evidence for an Improved 10-Item Version.
Not available
S-EPMC11299967 | biostudies-literature
Unknownabiliti Closed-Loop Gastric Electrical Stimulation System for Treatment of Obesity: Clinical Results with a 27-Month Follow-Up.
Not available
S-EPMC4559577 | biostudies-literature
TranscriptomicsBmp-regulated cardiac genes in zebrafish
The aim of this study was to identify genes that are regulated by Bmp signaling with the zebrafish heart at the heart cone stage around 21-23 hours post fertilization. In total, 4 samples based on cDNA from extracted cardiac tissue were analyzed: 2 samples of Tg(hsp70l:bmp2b)fr13 transgenic embryos ...
ORGANISM(S): Danio rerio 
2013-03-25 | E-GEOD-43888 | biostudies-arrayexpress
ProteomicsBSO and Auranofin Redox ICAT: Dataset of peptide identification results from a Redox ICAT experiment including rawfiles from LTQ-Orbitrap XL
In the current study, we used a mass spectrometry-based redox proteomics approach to test responses of the cysteine (Cys) proteome to selective disruption of the Trx- and GSH-dependent systems. Auranofin (ARF) was used to inhibit Trx reductase without detectable oxidation of the GSH/GSSG couple, and...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD000353 | Pride
Bso Auranofin Mass spectrometry Redox Icat Proteomics 
UnknownTopographic controls of soil organic carbon on soil-mantled landscapes.
Not available
S-EPMC6478868 | biostudies-literature
UnknownLeukemia reconstitution in vivo is driven by cells in early cell cycle and low metabolic state.
Not available
S-EPMC6058781 | biostudies-literature
ProteomicsRat Cortical Primary Neuronal Culture with NRN1 Protein Treatment
Cortical rat neuronal culture, lysis and proteolytic digestion Primary rat cortical neurons were generated from E18 Sprague-Dawley rat embryos with minor modifications (Swanger, Mattheyses et al. 2015, Henderson, Greathouse et al. 2019). Neurons were cultured at a density of 4x105 cells per well in...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-07-20 | PXD040867 | Pride
Rat primary cortical neurons Nrn1 Neuroproteomics 
ProteomicsPosttranslational modifications mediate the structural diversity of tauopathy strains
Tau aggregation is the defining pathological hallmark of tauopathies, but structural insights are revealing key differences between filaments across this class of disorders. Using cryo-electron microscopy, we identify a 107-residue fragment, K274-E380, which forms the insoluble core of tau filaments...
ORGANISM(S): Homo sapiens (Human) 
2020-02-14 | PXD016862 | Pride
Cbd Tau Mass spectrometry 
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