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TranscriptomicsThe Kinase SGK1 in the Endoderm and Mesoderm Promotes Ectodermal Survival by Downregulating Components of the Death-Inducing Signaling Complex
A balance between cell survival and apoptosis is essential for animal development. Although proper development involves multiple interactions between germ layers, little is known about the intercellular and intertissue signaling pathways that promote cell survival in neighboring or distant germ laye...
ORGANISM(S): Xenopus laevis 
2011-02-21 | E-GEOD-26381 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat kidney samples from Dahl SS/J and Sprague Dawley animals placed on high salt and basal salt diets
Serum and glucocorticoid-induced kinase 1 (SGK1) activates the epithselial sodium channel (eNaC) in tubules. We examined renal SGK1 abundance in salt-adaptation and in salt-sensitive hypertension. Sprague-Dawley and Dahl salt-sensitive rats were placed on either 8% or 0.3% NaCl diets for 10 days. Pl...
ORGANISM(S): Rattus norvegicus 
2007-10-11 | E-GEOD-599 | biostudies-arrayexpress
ProteomicsPlacental growth factor mediates pathological uterine vasculature by activating the NFAT5-SGK1 mechano-signaling axis in the endometrium: Implications for pre-eclampsia development.
After menstruation the uterine spiral arteries are repaired through angiogenesis. This process is tightly regulated by the paracrine communication between endometrial stromal cells (EnSCs) and endothelial cells. Any molecular aberration in these processes can lead to complications in pregnancy inclu...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD051697 | Pride
Pre-eclampsia Endometrium Sgk1 Pregnancy Placentation Mechanobiology Plgf 
GenomicsOptimizing the use of in vitro Transcribed SGK1-mRNA as a therapeutic tool to treat female infertility
IvtmRNA and SGK1
PRJEB88920 | ENA
GenomicsSGK1 Mediates TGF-β1-Induced Epithelial-Mesenchymal Transition and Fibrosis in Experimental Bronchiolitis Obliterans
SGK1 Mediates TGF-β1-Induced Epithelial-Mesenchymal Transition and Fibrosis in Experimental Bronchiolitis Obliterans
PRJNA1474801 | ENA
GenomicsGenome-wide analysis of mouse glial cell gene expression by Sgk1 inhibition.
Genome-wide analysis of mouse glial cell gene expression by Sgk1 inhibition.
PRJNA607297 | ENA
GenomicsSGK1 Mediates TGF-β1-Induced Epithelial-Mesenchymal Transition and Fibrosis in Experimental Bronchiolitis Obliterans [SGK]
SGK1 Mediates TGF-β1-Induced Epithelial-Mesenchymal Transition and Fibrosis in Experimental Bronchiolitis Obliterans [SGK]
PRJNA1537686 | ENA
ProteomicsCharacterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation
Despite significant progress, our understanding of how specific oncogenes transform cells is still limited and likely underestimates the complexity of downstream signalling events. Herein, we describe a novel, integrated approach that addresses this knowledge gap. This utilizes mass spectrometry-bas...
ORGANISM(S): Homo sapiens (Human) 
2019-01-14 | PXD010687 | Pride
Breast cancer Cancer Src Kinome 
GenomicsExpression data from kidney cortex of control and transgenic sgk1 mice under DOCA/NaCl treatment
Expression data from kidney cortex of control and transgenic sgk1 mice under DOCA/NaCl treatment
PRJNA626015 | ENA
TranscriptomicsSGK1 Mediates TGF-β1-Induced Epithelial-Mesenchymal Transition and Fibrosis in Experimental Bronchiolitis Obliterans
Bronchiolitis obliterans (BO) represents a major complication limiting long-term survival after lung transplantation, with epithelial-mesenchymal transition (EMT) serving as a core pathogenic mechanism. The TGF-β1 signaling pathway plays a critical role in EMT induction and can activate serum/glucoc...
ORGANISM(S): Mus musculus 
2026-09-24 | GSE334327 | GEO
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