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ProteomicsPresentation of DNAJB1-PRKACA fusion neoantigens by different HLA class I alleles
Fibrolamellar carcinoma (FLC) is a liver tumor with a high mortality burden and few treatment options. A promising therapeutic vulnerability in this disease is its highly conserved driver mutation: a gene fusion between DNAJB1 and PRKACA, which is expressed in virtually all FLC tumors and could be a...
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD042316 | Pride
Fusion neoantigens Hla class i Cd8 t cell Dnajb1-prkaca Fibrolamellar carcinoma 
ProteomicsApolipoprotein A-II Increases Cholesterol Efflux Capacity of Mature High-Density Lipoproteins Via the Apolipoprotein A-I C-terminus
Samples were processed using Global and Limited Proteolysis (LiP). Peptides and proteins were identified using MaxQuant (v1.6.17.0), then summarized using R package RomicsProcessor.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-07-29 | MSV000095479 | MassIVE
UnknownAssociation of ACE Gene I/D polymorphism with migraine in Kashmiri population.
Not available
S-EPMC4782560 | biostudies-literature
UnknownData on microRNAs and microRNA-targeted mRNAs in Xenopus ectoderm.
Not available
S-EPMC5079235 | biostudies-literature
ProteomicsProteogenomic identification of Hepatitis B virus (HBV) genotype-specific HLA-I restricted peptides from HBV-positive patient liver tissues
The presentation of virus-derived peptides by HLA class I molecules on the surface of an infected cell and the recognition of these HLA-peptide complexes by, and subsequent activation of, CD8+ cytotoxic T cells provides an important mechanism for immune protection against viruses. Recent advances in...
ORGANISM(S): Homo sapiens (Human) 
2023-01-03 | PXD037270 | Pride
Proteogenomics Hepatocellular carcinoma Hepatitis b Human leukocyte antigen (hla) Immunopeptidomics 
UnknownBroad-spectrum resistance against multiple PVY-strains by CRSIPR/Cas13 system in Solanum tuberosum crop.
Not available
S-EPMC9176253 | biostudies-literature
UnknownEffects of Eurycoma longifolia Jack standardised water extract (Physta) on well-being of perimenopausal and postmenopausal women: protocol for a randomised, double-blinded, placebo-controlled, parallel group study.
Not available
S-EPMC10626840 | biostudies-literature
UnknownA novel mutation in the endothelin B receptor gene in a moroccan family with shah-waardenburg syndrome.
Not available
S-EPMC4369116 | biostudies-literature
GenomicsSFPQ depletion is synthetically lethal with BRAFV600E in colorectal cancer cells I
SFPQ depletion is synthetically lethal with BRAFV600E in colorectal cancer cells I
PRJNA479751 | ENA
UnknownNew ferrocene integrated amphiphilic guanidines: Synthesis, spectroscopic elucidation, DFT calculation and in vitro α-amylase and α-glucosidase inhibition combined with molecular docking approach.
Not available
S-EPMC10102212 | biostudies-literature
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