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ProteomicsSystems toxicology assessment of CHTP1.2 [Liver Data]
Modified risk tobacco products (MRTPs) have the potential to reduce smoking-related health risks. The Carbon Heated Tobacco Product 1.2 (CHTP1.2) is a potential MRTP that uses a pressed carbon heat source to generate an aerosol by heating tobacco. This study reports the results from the systems toxi...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-03-19 | PXD008423 | Pride
Rat Mrtp Itraq Lc-msms Systems toxicology 
ProteomicsSystems toxicology assessment of CHTP1.2 [RNE Data]
Modified risk tobacco products (MRTPs) have the potential to reduce smoking-related health risks. The Carbon Heated Tobacco Product 1.2 (CHTP1.2) is a potential MRTP that uses a pressed carbon heat source to generate an aerosol by heating tobacco. This study reports the results from the systems toxi...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-03-19 | PXD008424 | Pride
Rat Mrtp Itraq Lc-msms Systems toxicology 
ProteomicsSystems toxicology assessment of CHTP1.2 [Lung Data]
Modified risk tobacco products (MRTPs) have the potential to reduce smoking-related health risks. The Carbon Heated Tobacco Product 1.2 (CHTP1.2) is a potential MRTP that uses a pressed carbon heat source to generate an aerosol by heating tobacco. This study reports the results from the systems toxi...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-03-19 | PXD008422 | Pride
Rat Mrtp Itraq Lc-msms Systems toxicology 
ProteomicsShort-term blockade of pro-inflammatory alarmin S100A9 fa-vorably modulates left ventricle proteome and related signaling pathways involved in post – myocardial infarction recovery
Prognosis after myocardial infarction (MI) varies greatly depending of the extent of damaged area and the management of biological processes during recovery. Reportedly, the inhibition of the pro-inflammatory S100A9 reduces myocardial damage after MI. We hypothesize that S100A9 blockade induces chan...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-19 | PXD033683 | Pride
Hypertrophy Apoptosis Cardiac repair S100a9 Myocardial infarction 
UnknownBreath metabolome of mice infected with Pseudomonas aeruginosa.
Not available
S-EPMC6537093 | biostudies-literature
UnknownExploration of the Transcriptional Landscape of ALPPS Reveals the Pathways of Accelerated Liver Regeneration.
Not available
S-EPMC6882302 | biostudies-literature
GenomicsThr172 phospho-AMPK ChIP-seq in mouse liver
The aim of the experiment is to define p-AMPK binding sites across the genome upon mice starvation and treatment with Dexamethasone (GR ligand) and GW7647 (PPAR alpha ligand).
ORGANISM(S): Mus musculus 
2020-10-01 | E-MTAB-7301 | biostudies-arrayexpress
ProteomicsRespiratory effects of exposure to aerosol from the candidate modified-risk tobacco product THS 2.2 in an 18-month systems toxicology study with A/J mice [Lung data]
Smoking cessation is the most effective measure for reducing the risk of smoking-related diseases but switching to less harmful products (modified-risk tobacco products) can be an alternative for smokers who would otherwise not quit. In an 18-month chronic carcinogenicity/toxicity study in A/J mice ...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-13 | PXD016460 | Pride
Lc-msms Mouse Lung Systems toxicology Itraq 
ProteomicsRespiratory effects of exposure to aerosol from the candidate modified-risk tobacco product THS 2.2 in an 18-month systems toxicology study with A/J mice [RNE data]
Smoking cessation is the most effective measure for reducing the risk of smoking-related diseases but switching to less harmful products (modified-risk tobacco products) can be an alternative for smokers who would otherwise not quit. In an 18-month chronic carcinogenicity/toxicity study in A/J mice ...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-13 | PXD016466 | Pride
Lc-msms Respiratory nasal epithelium Mouse Systems toxicology Itraq 
TranscriptomicsEffect of Ovarian Hormone on Gene Expression in Laser Captured Serotonin Neurons from Monkeys
Ovariectomized monkeys were treated with placebo, estrogen or estrogen plus progesterone for one month. The brain was perfused with RNA Later plus 20% sucrose. Sections through the dorsal raphe nucleus were immunostained for TPH and then TPH positive neurons were laser captured. The RNA was extracte...
ORGANISM(S): Macaca mulatta 
2010-04-08 | E-GEOD-16169 | biostudies-arrayexpress
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