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MetabolomicsAspSnFR: A Genetically-Encoded Biosensor for Real-Time Monitoring of Aspartate in Live Cells

Aspartate is crucial for nucleotide synthesis, ammonia detoxification and maintaining redox balance via the malate-aspartate-shuttle (MAS). To disentangle these multiple roles of aspartate metabolism, tools are required that measure aspartate concentrations in real time and in live cells. We intr...

2024-08-27 | MTBLS10035 | MetaboLights
TranscriptomicsDNA methylation data from primary neuroblastoma tumors
Genome wide DNA methylation profiling of primary neuroblastomas. The Illumina 450k methylation array was used to obtain DNA methylation profiles across approximately 485,000 CpGs in 105 neuroblastomas. Tumors were derived from 40 low-risk, 9 intermediate-risk and 56 high-risk patients. Bisulphite c...
ORGANISM(S): Homo sapiens 
2016-09-08 | E-GEOD-73515 | biostudies-arrayexpress
GenomicsA global change in RNA Polymerase II pausing during the Drosophila midblastula transition
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2013-07-25 | E-GEOD-41703 | biostudies-arrayexpress
GenomicsDifferent transcriptional strategies for zygotic genome activation in Drosophila [MNase-Seq]
During animal development, a fertilized egg is initially under the control of maternal products and only starts zygotic transcription after several cell divisions. In animals such as Xenopus, zebrafish and Drosophila, a massive increase in zygotic transcription occurs during the mid-blastula transit...
ORGANISM(S): Drosophila melanogaster 
2013-07-26 | E-GEOD-41686 | biostudies-arrayexpress
ProteomicsStructure and mechanism of CSP secretion pump of ComA for Quorum sensing
Cross-linking MS data for 1) ComA Apo form and 2) ComA +ATP form. Purified proteins were cross-linked with DSSO, digested with either trypsin or chymotrypsin, and acquired by MS2-MS3 acquisition method. 2 technical replicates were acquired for each digested sample.
ORGANISM(S): Cellular Organisms 
2023-08-31 | PXD038058 | JPOST Repository
ProteomicsIntact Mass analysis of class III lanthipeptide PneA
Intact Mass analysis of PneA under various modification states
ORGANISM(S): Streptococcus Pneumoniae Pt8114 
2024-08-13 | PXD050940 |
ProteomicsProteomics quantitative analysis of lung tissues in silica-exposed rats
Proteomics quantitative analysis of lung tissues from silica-exposed rats to reveal the pathogenesis of silicosis and provide potential therapeutic targets.
ORGANISM(S): Rattus Norvegicus 
2020-07-29 | PXD020625 |
Genomicsena-DATASET-UCL-ICH-25-11-2015-12:32:35:398-26 - samples
Description not provided
EGAD00001001687 | EGA
GenomicsTelomerase activation by genomic rearrangements in high-risk neuroblastoma
Neuroblastoma is a malignant pediatric tumor of the sympathetic nervous system1. Roughly half of these tumors regress spontaneously or are cured by limited therapy. By contrast, high-risk neuroblastomas have an unfavorable clinical course despite intensive multimodal treatment, and their molecular b...
EGAS00001001308 | EGA
GenomicsDAC University Hospital Cologne
Data Access Committee EGAC00001000361
EGAC00001000361 | EGA
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