Sort   by:  
 Page size 
ProteomicsA novel dual histone mark reader ZCWPW2 regulates meiotic recombination through lactylation and transcriptional control in humans and mice
Meiotic recombination ensures proper chromosome segregation and genetic diversity during gametogenesis, and its disruption leads to infertility. It is known that the dual histone methylation writer–reader system, in which PRDM9 deposits H3K4me3 and H3K36me3 marks at nucleosomes to specify recombinat...
ORGANISM(S): Homo sapiens (Human) 
2026-01-07 | PXD070427 | Pride
Meiotic recombination  zcwpw1–zcwpw2 complex  prdm9/zcwpw1/zcwpw2 system  ldha  ep300  lactylation 
UnknownSocial Coordination Information in Dynamic Chase Modulates EEG Mu Rhythm.
Not available
S-EPMC5500576 | biostudies-literature
ProteomicsA novel dual histone mark reader ZCWPW2 regulates meiotic recombination through lactylation and transcriptional control in humans and mice
Meiotic recombination ensures proper chromosome segregation and genetic diversity during gametogenesis, and its disruption leads to infertility. It is known that the dual histone methylation writer–reader system, in which PRDM9 deposits H3K4me3 and H3K36me3 marks at nucleosomes to specify recombinat...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-01-07 | PXD068838 | Pride
Meiotic recombination  zcwpw1–zcwpw2 complex  prdm9/zcwpw1/zcwpw2 system  ldha  ep300  lactylation 
UnknownMachine Learned Classification of Ligand Intrinsic Activities at Human μ-Opioid Receptor.
Not available
S-EPMC12341632 | biostudies-literature
UnknownThe molecular basis of μ-opioid receptor signaling plasticity.
Not available
S-EPMC12689640 | biostudies-literature
UnknownMachine Learned Classification of Ligand Intrinsic Activities at Human <i>μ</i>-Opioid Receptor.
Not available
S-EPMC11030315 | biostudies-literature
MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
ProteomicsSchistosoma japonicum cercaria and schistosomula
Schistosomiasis is a parasitic zoonosis which caused by schistosomes and poses great threat to the health of human and other mammals. Schistosome cercaria must penetrate skin as an initial step to successfully infect the final host. Proteolytic enzymes secreted from the acetabular glands of cercaria...
ORGANISM(S): Caenorhabditis elegans 
2017-05-08 | PXD002185 | Pride
Schistosomula Cercaria Proteome Schistosoma japonicum 
ProteomicsTowards a universal sample preparation method for denaturing top-down proteomics of complex proteomes
A universal and standardized sample preparation method becomes vital for denaturing top-down proteomics (dTDP) to advance the scale and accuracy of proteoform delineation in complex biological systems. It needs to have high protein recovery, minimum bias, good reproducibility, and compatibility with...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2020-05-22 | PXD018248 | Pride
Histone Ptms Membrane ultrafiltration Chloroform-methanol precipitation Membrane proteins Sp3 Denaturing top-down proteomics Cze-ms/ms Sds Sample preparation 
UnknownEnhancing Hydrogen Adsorption Capacity of Metal Organic Frameworks M(BDC)TED0.5 through Constructing a Bimetallic Structure.
Not available
S-EPMC9201887 | biostudies-literature
Sort   by:  
 Page size