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ProteomicsComprehensive Proteomic Characterization of Scar Formation in Urethral Stricture Disease
Male urethral stricture disease (USD) is characterized by scar formation, whose molecular mechanism is still lack. In this study, we performed comprehensive proteomic landscape of USD with 12 scar tissues and 5 matched normal adjacent tissues (NATs). Comparative analysis disclosed the ECM signaling ...
ORGANISM(S): Homo Sapiens 
2024-06-18 | PXD053186 |
ProteomicsProteomic and phosphoproteomic profiling of original, Delta, or Omicron strain SARS-CoV-2-infected lung of rhesus macaque
The Omicron variant, mutated from the original SARS-CoV-2 strain, is still circulating worldwide. We performed LC-MS based proteome and phosphoproteome analysis using lung tissues separated from rhesus monkeys, which were infected with Omicron, the original virus or one of the VOCs, the Delta varian...
ORGANISM(S): Macaca Mulatta 
2023-12-12 | PXD047779 |
ProteomicsGlobal profiling of the proteome and acetylome in mice with abdominal aortic aneurysms
Abdominal Aortic Aneurysm (AAA) is a fatal vascular disease characterized by abnormal expansion of the arterial wall and a high risk of rupture. Current treatments for AAA primarily rely on surgical intervention, while effective pharmacological therapies have yet to be developed. The major bottlenec...
ORGANISM(S): Mus Musculus 
2025-02-17 | PXD060895 |
ProteomicsA comprehensive proteome and phosphoproteome atlas across nine organs of the Chinese hamster
We present the first comprehensive proteomic and phosphoproteomic atlas of nine major organs of the Chinese hamster (Cricetulus griseus). A total of 14,219 proteins, 11,828 phosphorylated proteins, and 47,122 phosphorylation sites were identified, revealing distinct inter-organ molecular features.
ORGANISM(S): Cricetulus Griseus 
2025-10-04 | PXD069241 |
ProteomicsThe eWAT ubiquitinome of wild type mice and Mdm2 adipocyte-specific knock-in mice fed high-fat diet
The epididymal adipose tissue (eWAT) samples from wild type mice fed high-fat diet for 12 weeks (H_WT_E) and Mdm2 adipocyte-specific knock-in mice fed high-fat diet for 12 weeks (H_KI_E) were mixed separately, and subjected to ubiquitinome study by Label-free quantification and ubiquitination modifi...
ORGANISM(S): Mus Musculus 
2022-05-26 | PXD034127 |
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