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ProteomicsChemical cross-linking enables drafting ClpXP proximity maps and taking snapshots of in vivo interaction networks
Protein-protein interactions within complexes and networks are often dynamic and their elucidation remains a challenging task. Here, we show on the example of the proteolytic ClpXP complex the power of combined chemical cross-linking and mass-spectrometry to capture transient binding interactions wi...
ORGANISM(S): Homo sapiens (Human) Escherichia coli Staphylococcus aureus 
2018-11-21 | PXD009224 | Pride
Clpxp Interacting proteins Chemical cross-linking Co-ip Clpp 
UnknownVarying Responses to Heat Stress and Salinization Between Benthic and Pelagic Riverine Microbial Communities.
Not available
S-EPMC12411665 | biostudies-literature
UnknownParkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program.
Not available
S-EPMC5619098 | biostudies-literature
TranscriptomicsRobust Molecular Classification of Ependymal Tumors Across All Anatomic Compartments
Ependymal tumors across age groups have been classified solely by histopathology. It is, however, commonly accepted that this classification has limited clinical utility based on its poor reliability. We aimed at establishing a reliable and reproducible molecular classification using DNA methylation...
ORGANISM(S): Homo sapiens 
2015-05-21 | E-GEOD-65362 | biostudies-arrayexpress
UnknownPrognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort.
Not available
S-EPMC7338015 | biostudies-literature
Genomics2013-11-19-17-24-36-breez-MB-2013-10-18-Whole_exome_DNAseq_Medulloblastoma - samples
Illumina HiSeq sequence data (with >80x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed. The whole exome sequencing data of 20 SHH medulloblastomas ...
EGAD00001000698 | EGA
TranscriptomicsColorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer
Human colorectal cancer (CRC) cell lines are a used widely-used to model system for investigation investigate of tumour biology, experimental therapytherapeutic and biomarkers discovery. However, to what extent these established CRC cell lines represent and maintain the genetic diversity of primary ...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-55832 | biostudies-arrayexpress
GenomicsPCGP MB WGS Full - samples
DATA FILES FOR PCGP MB WGS - Supersedes (EGAD00001000269)
EGAD00001001864 | EGA
GenomicsPCGP MB - samples
OLD DATA FILES FOR SJMB - Superseded by EGAD00001001864
EGAD00001000269 | EGA
GenomicsGenetic landscape of pediatric Medulloblastoma
Medulloblastoma is a heterogenous disease made up of at least four distinct subtypes of disease which appear to exploit and disrupt naturally occurring developmental pathways of cellular growth and hindbrain development. To better understand the driver mutations of this disease, we performed whole g...
EGAS00001000347 | EGA
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