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ProteomicsIdentification of Siglec-7-ligand candidates on JVM-3 human B cell line by proximity labeling
Siglec-7 is a member of Siglec family of glycan recognition proteins involved in the regulation of natural killer (NK) cell activities. We found Siglec-7 ligand is highly expressed on JVM-3, a B cell chronic lymphocytic leukemia (B-CLL) cell line. In this experiment, we attempted at identifying th...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD024690 | Pride
Human Lc-msms Siglec-7 Ligand B cell Sialic acid 
UnknownSialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9.
Not available
S-EPMC7904912 | biostudies-literature
UnknownSiglec-7 on peripheral blood eosinophils: Surface expression and function.
Not available
S-EPMC6661208 | biostudies-literature
UnknownSialylated glycoproteins suppress immune cell killing by binding to Siglec-7 and Siglec-9 in prostate cancer.
Not available
S-EPMC11645153 | biostudies-literature
UnknownRole of Siglec-7 in apoptosis in human platelets.
Not available
S-EPMC4167548 | biostudies-literature
UnknownSiglec-7 and Siglec-9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling.
Not available
S-EPMC11378723 | biostudies-literature
UnknownIdentification and functional characterization of a Siglec-7 counter-receptor on K562 cells.
Not available
S-EPMC8040268 | biostudies-literature
UnknownDiscovery of a new sialic acid binding region that regulates Siglec-7.
Not available
S-EPMC7250851 | biostudies-literature
ProteomicsSiglec-7 inhibits TLR3-induced pro-inflammatory cytokine production from human monocytes and macrophages
Immune checkpoint receptors, including Sialic-acid-binding immunoglobulinlike lectins (Siglecs), are critical regulators of immune homeostasis. Siglecs can serve as negative regulators of Toll-like receptor (TLR) signaling, promoting the resolution of inflammatory signaling through feedback inhibiti...
ORGANISM(S): Homo Sapiens (human) 
2026-03-05 | PXD075217 | JPOST Repository
UnknownThe glycoimmune checkpoint receptor Siglec-7 interacts with T-cell ligands and regulates T-cell activation.
Not available
S-EPMC10831161 | biostudies-literature
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