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NtrC-like activators regulate transcription of a wide variety of adaptive genes in bacteria. Previously we demonstrated that a mutation in the NtrC-like activator gene nla18 severely inhibits M. xanthus fruiting body development and vegetative growth. In this study, we found that inactivation of n...
ORGANISM(S): Myxococcus xanthus 
Phosphate regulation is complex in the developmental prokaryote Myxococcus xanthus, and requires at least three previously characterized two-component systems (TCS), designated PhoR1-PhoP1, PhoR2-PhoP2, and PhoR3-PhoP3. We report here the identification and characterization of a member of a fourth ...
ORGANISM(S): Myxococcus xanthus 
Humans are exposed to a wide range of exogenous and endogenous alkylating agents, including agents frequently used as cytostatic drugs in cancer treatment (Drablos, Feyzi et al. 2004). Alkylating agents are mutagenic and cytotoxic and the major body of research has focused on their effects upon DNA....
ORGANISM(S): Homo sapiens (Human) 
2021-08-30 | PXD003549 | Pride
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