Sort   by:  
 Page size 
TranscriptomicsCSR-1 and P granules suppress sperm-specific transcription in the C. elegans germline
P granules in C. elegans are required for fertility and function to maintain germ cell identity and pluripotency.  Sterility in the absence of P granules is often accompanied by the mis-expression of soma-specific proteins and the initiation of somatic differentiation in germ cells.  To investigate ...
ORGANISM(S): Caenorhabditis elegans 
2015-05-20 | E-GEOD-67954 | biostudies-arrayexpress
GenomicsSingle Methanogenic Granules
Single Granules as highly-replicated whole-ecosystems
PRJEB29753 | ENA
ProteomicsIdentification of a novel class of cytotoxic granules as origin of supramolecular attack particles in T lymphocytes
Cytotoxic T lymphocytes (CTL) kill malignant and infected cells via cytotoxic proteins such as granzyme B (GzmB) that are released into the immunological synapse in the form of ~110 nm supramolecular attack particles (SMAPs). However, it is not known where SMAPs are stored in the cell and how they a...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-04 | PXD025055 | Pride
Exocytosis Proteomics Snare proteins Immunological synapse Cytotoxic granules Single core granules Supramolecular attack particles Total internal reflection fluorescence microscopy Correlative light and electron microscopy Multi core granules 
TranscriptomicsECT2 and AURKB Modulate Formation of Stress Granules Containing Transcripts from Diverse Cellular Pathways in Astrocytoma Cells
Stress granules are small RNA-protein granules that modify the translational landscape during cellular stress to promote survival. The RhoGTPase RhoA is implicated in the formation of RNA stress granules. Our data demonstrate that the cytokinetic proteins ECT2 and AurkB are localized to stress gran...
ORGANISM(S): Homo sapiens 
2016-02-29 | E-GEOD-76814 | biostudies-arrayexpress
ProteomicsGermline maintenance through the multifaceted activities of GLH/Vasa in Caenorhabditis elegans P granules
Vasa is a highly conserved member of the ATP-dependent DEAD box helicase family, a multipotency factor, and a critical component for the specification and maintenance of the germline. Its homologs have been shown to regulate translation, small RNA amplification, and serve as a molecular solvent for ...
ORGANISM(S): Caenorhabditis elegans 
2019-06-07 | PXD014135 | Pride
Vasa C. elegans Glh-1 Glh-1 coip 
TranscriptomicsDistinct Dynamics and Composition of Endogenous Neuronal RNA Granules
RNA granules are essential regulators of post-transcriptional gene expression, enabling mRNA transport, localization and local translation in neurons. The localized transcriptome is diverse; however, how different mRNAs are organized into granules for efficient localization and translation remains u...
ORGANISM(S): Mus musculus 
2026-04-01 | GSE326430 | GEO
GenomicsDistinct Dynamics and Composition of Endogenous Neuronal RNA Granules
Distinct Dynamics and Composition of Endogenous Neuronal RNA Granules
PRJNA1445255 | ENA
UnknownFlow cytometry-assisted purification and proteomic analysis of the corticotropes dense-core secretory granules.
Not available
S-EPMC2989539 | biostudies-literature
UnknownIdentification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes.
Not available
S-EPMC8873490 | biostudies-literature
UnknownDynamic Recruitment of Single RNAs to Processing Bodies Depends on RNA Functionality.
Not available
S-EPMC6499680 | biostudies-literature
Sort   by:  
 Page size