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ProteomicsCross-linking mass spectrometric analysis of Ska-MT interactions
This project is about characterizing the interaction of the MT-binding domains (MTBD) of the human Ska complex with MTs by cross-linking mass spectrometry
ORGANISM(S): Homo sapiens (Human) 
2016-01-28 | PXD003502 | Pride
Cross-linking Microtubules Ska complex Lc-ms/ms 
ProteomicsMps1 regulates kinetochore-microtubule attachment stability via the Ska complex to ensure error-free chromosome segregation
Spindle assembly checkpoint (SAC) regulators such as the Mps1 kinase not only delay anaphase onset, but also correct improper chromosome-spindle linkages that would otherwise lead to missegregation and aneuploidy. However, the substrates and mechanisms involved in this pathway of error correction re...
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD006135 | Pride
Proteomics Mps1 Chemical genetics Ska complex Spindle assembly checkpoint (sac) Pp2a-b56 
UnknownOverexpression of SKA Complex Is Associated With Poor Prognosis in Gliomas.
Not available
S-EPMC8791909 | biostudies-literature
UnknownStructural basis for microtubule recognition by the human kinetochore Ska complex.
Not available
S-EPMC3923297 | biostudies-literature
UnknownThe Ska complex promotes Aurora B activity to ensure chromosome biorientation.
Not available
S-EPMC5057281 | biostudies-literature
UnknownPhosphatase-regulated recruitment of the spindle- and kinetochore-associated (Ska) complex to kinetochores.
Not available
S-EPMC5703607 | biostudies-literature
UnknownStable kinetochore-microtubule interactions depend on the Ska complex and its new component Ska3/C13Orf3.
Not available
S-EPMC2669960 | biostudies-literature
UnknownDephosphorylation of the Ndc80 Tail Stabilizes Kinetochore-Microtubule Attachments via the Ska Complex.
Not available
S-EPMC5572820 | biostudies-literature
ProteomicsSka3-microtubule interactions - Ska3 Ensures Timely Mitotic Progression by Interacting Directly With Microtubules and Ska1 Microtubule Binding Domain
The Ndc 80 and Ska complex are the major microtubule-binding factors of the kinetochore responsible for maintaining chromosome-microtubule coupling during chromosome segregation. We previously showed that the Ska1 subunit of the Skacomlex binds dynamic microtubules. This project demonstrated that Sk...
ORGANISM(S): Homo sapiens (Human) 
2016-10-03 | PXD004952 | Pride
Microtubule Ska complex 
UnknownMechanism of Ska Recruitment by Ndc80 Complexes to Kinetochores.
Not available
S-EPMC5926205 | biostudies-literature
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