Sort   by:  
 Page size 
OtherKnockdown and overexpression of SLC3A2 in MCF10A cells
To knock down SLC3A2, MCF10A cells were either transfected with control siRNAs, or siRNAs specifically targetting SLC3A2. Samples were either untreated or treated with TGFb. Ribosome profiling and RNA sequencing was performed on these samples. MCF10A cells with and without SLC3A2 overexpression cons...
ORGANISM(S): Homo sapiens 
2017-07-27 | GSE59818 | GEO
GenomicsComparative analysis of gene expression of SLC3A2 monoallelic knockout and wild type clones
Comparative analysis of gene expression of SLC3A2 monoallelic knockout and wild type clones
PRJNA477517 | ENA
ProteomicsMouse brain endothelial cells LC-MS/MS
In our study, we used immunofluorescence to examine brain endothelial cells (ECs) from Slc3a2 ECKO mice and found that blood-brain barrier markers, including tight junction proteins and transcytosis-associated proteins, exhibited significant changes compared to Slc3a2 WT mice. To further investigate...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-27 | PXD064613 | Pride
Endothelial cells Blood-brain barrier Mouse Brain Lc-ms/ms 
ProteomicsCharacterization of RAS and SLC3A2 signaling in multiple myeloma
Oncogenic mutations within the RAS pathway are common in multiple myeloma (MM), an incurable malignancy of plasma cells. However, the mechanisms of pathogenic RAS signaling in this disease remain enigmatic and difficult to inhibit therapeutically. We employed an unbiased proteogenomic approach to ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD031662 | Pride
Phosphoproteomes Nras Kras Slc3a2 Bioid2 Multiple myeloma 
TranscriptomicsCancer SLC3A2-mediated lysine uptake restricts T cell immunity against hepatocellular carcinoma
Our research demonstrates that in hepatocellular carcinoma (HCC), tumor cells outcompete T cells for lysine (Lys) by overexpressing the SLC3A2 transporter, thereby reducing Lys availability within the tumor microenvironment. This lysine deprivation results in decreased STAT3 levels in T cells, inhib...
ORGANISM(S): Homo sapiens Mus musculus 
2024-12-23 | GSE284633 | GEO
GenomicsLiquid-liquid phase separation of ZHX2 protects DLBCL cells against ferroptosis through induction of SLC3A2
Liquid-liquid phase separation of ZHX2 protects DLBCL cells against ferroptosis through induction of SLC3A2
PRJNA1240601 | ENA
UnknownAnaplastic Lymphoma Kinase signaling stabilizes SLC3A2 expression via MARCH11 to promote neuroblastoma cell growth.
Not available
S-EPMC11239919 | biostudies-literature
GenomicsHomo sapiens
Knockdown and overexpression of SLC3A2 in MCF10A cells
PRJNA256318 | ENA
UnknownSLC3A2 promotes tumor-associated macrophage polarization through metabolic reprogramming in lung cancer.
Not available
S-EPMC10236635 | biostudies-literature
UnknownCharacterizing the role of SLC3A2 in the molecular landscape and immune microenvironment across human tumors.
Not available
S-EPMC9388758 | biostudies-literature
Sort   by:  
 Page size