Small extracellular vesicles (sevs)

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Unknown (832)
Genomics (155)
Proteomics (117)
Transcriptomics (53)
Other (2)
Metabolomics (2)

Organisms

Aerococcus urinae NBRC 15544 = CCUG 36881 (94)
Andropogon gerardi (94)
Bacteria (94)
Bartonella quintana JK 31 (94)
Canis lupus familiaris (94)
Cnidaria (94)
Ectopseudomonas oleovorans CECT 5344 (94)
Ensifer adhaerens (94)
Halictus scabiosae (94)
Human immunodeficiency virus 1 (94)
Mesocricetus auratus (94)
Miscanthus x giganteus (94)
Mus musculus (94)
Panicum virgatum (94)
Pseudomonas aeruginosa SJTD-1 (94)
Rabies virus Nishigahara RCEH (94)
Rattus norvegicus (94)
Rattus rattus (94)
Rhodococcus jostii RHA1 (94)
Rhodopseudomonas palustris (94)
Schizosaccharomyces pombe 927 (94)
Shigella (94)
Sorghastrum nutans (94)
Staphylococcus aureus (94)
Homo sapiens (60)
Mus musculus (40)
Rattus norvegicus (8)
synthetic construct (4)
Equus caballus (1)
Bos taurus (1)

Organisms

Homo sapiens (61)
Mus musculus (30)
Rattus norvegicus (4)
Equus caballus (1)
Bos taurus (1)

Repository

ENA (117)
pride (94)
geo (87)
iProX (11)
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biostudies-arrayexpress (6)
jPOST (5)
MetaboLights (2)

Tissue

Cell culture (20)
Epithelial cell (13)
Blood plasma (10)
Brain (5)
Extracellular vesicle (5)
Blood serum (4)
Kidney (4)
Permanent cell line cell (4)
Embryonic stem cell (3)
T cell (3)
Blood (2)
Cell suspension culture (2)
Cerebrospinal fluid (2)
Colon (2)
Cytotoxic T-lymphocyte (2)
Fibroblast (2)
Liver (2)
Lymph node (2)
Pancreas (2)
Stem cell (2)
Adipose tissue (1)
Amniotic fluid (1)
Bone (1)
Bone marrow (1)
Brain microvascular endothelial cell (1)
Breast (1)
Breast cell line (1)
Breast epithelium (1)
Cell line cell (1)
Culture condition: dark grown cells (1)

Disease

Breast cancer (6)
Disease free (5)
Brain glioblastoma multiforme (3)
Brain cancer (2)
Glioblastoma (2)
Melanoma (2)
Pre-eclampsia (2)
Type 2 diabetes mellitus (2)
Antenatal onset (1)
Atopic dermatitis (1)
Breast adenocarcinoma (1)
Cancer (1)
Cataract (1)
Colon cancer (1)
Colorectal cancer (1)
Glaucoma (1)
Head and neck squamous cell carcinoma (1)
Human cytomegalovirus infection (1)
Human immunodeficiency virus infectious disease (1)
Hydronephrosis (1)
Hypersensitivity reaction type I disease (1)
Liver cirrhosis (1)
Lymphoma (1)
Male infertility (1)
Malignant neoplasm of ovary (1)
Oral cavity (1)
Osteoporosis (1)
Ovary epithelial cancer (1)
Pancreas adenocarcinoma (1)
Pancreatitis (1)

Technology Type

Mass Spectrometry (94)
Shotgun proteomics (46)
Bottom-up proteomics (29)
Data-dependent acquisition (16)
Data-independent acquisition (12)
Gel-based experiment (7)
Affinity purification coupled with mass spectrometry proteomics (3)
SWATH MS (3)
Mass spectrometry (2)
DiaPASEF (2)
Top-down proteomics (1)

Instrument Platform

Illumina HiSeq 2500 (5)
Illumina TruSeq Small RNA Sample kit (2)
TRIzol reagent (2)
Orbitrap Q Extractive Plus (2)
BD Vacutainer, 367814; ExoQuick (1)
NextSeq 500 (1)
LTQ Orbitrap Elite (1)
Orbitrap Fusion (1)
Q Exactive (1)
Q Exactive Plus (1)
QE-HF in DIA mode in the LC-MS/MS (1)
Liquid Chromatography MS - alternating - hilic (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - positive - reverse phase (1)

Publication Date

2025 (55)
2026 (39)
2024 (34)
2023 (28)
2022 (25)
2021 (18)
2020 (7)
2019 (4)
2017 (1)
2018 (1)

CHEBI ID

CHEBI:47979 (1)
CHEBI:189710 (1)
CHEBI:47878 (1)
CHEBI:17665 (1)
CHEBI:28013 (1)
CHEBI:191640 (1)
CHEBI:24344 (1)
CHEBI:5417 (1)
CHEBI:84634 (1)
CHEBI:21949 (1)
CHEBI:17822 (1)
CHEBI:26271 (1)
CHEBI:17202 (1)
CHEBI:30865 (1)
CHEBI:22660 (1)
CHEBI:27570 (1)
CHEBI:18186 (1)
CHEBI:26986 (1)
CHEBI:16811 (1)
CHEBI:17234 (1)
CHEBI:28300 (1)
CHEBI:16708 (1)
CHEBI:16742 (1)
CHEBI:17748 (1)
CHEBI:24898 (1)
CHEBI:25017 (1)
CHEBI:18009 (1)
CHEBI:15846 (1)
CHEBI:17754 (1)
CHEBI:28044 (1)

Metabolite Name

Acetyl-L-carnitine (2.0) (1)
N-Ac-Muramate (1)
N-Ac-Glucosamine-6P (1)
N-Ac-Glucosamine (1)
OphthalmicAcid (1)
Butyryl-L-carnitine (4.0) (1)
Hexanoyl-L-carnitine (6.0) (1)
S-Adenosyl-Homocysteine (1)
S-Adenosyl-Methionine (1)
UDP-N-Ac-Glucosamine (1)
Myristoyl-L-carnitine (14.0) (1)
AcetylCoA (1)
Palmitoyl-L-carnitine (16.0) (1)
Stearoyl-L-carnitine (18.0) (1)
B-ALA (1)
Glyceraldehyde3P (1)
Dihydroxyacetone3P (1)
2P-glycerate (1)
Erythrose4P (1)
Ribulose5P (1)
A-Ketoglutarate (1)
N-Carbamoyl-aspartate (1)
HexP (1)
Fructose16bisP (1)
N-Acetylglutamate (1)
Sedoheptulose7P (1)
Oleoyl-L-carnitine (18.1) (1)
MET (1)
GLY (1)
ASP (1)

First Public Date

2025 (39)
2024 (23)
2026 (21)
2023 (11)
2022 (8)
2021 (7)
2020 (4)
2019 (3)
2017 (1)

Study type

RNA-seq of coding RNA (4)
MicroRNA profiling by high throughput sequencing (1)
RNA-seq of non coding RNA (1)

Release Date

2025 (180)
2023 (157)
2022 (145)
2024 (128)
2021 (108)
2020 (58)
2026 (27)
2019 (24)
2018 (5)
2017 (5)
2016 (1)

Lab affiliation

Department of Chemistry and Biomolecular Sciences, University of Ottawa, Canada (3)
Head of the Curie Institute Mass Spectrometry Platform (3)
Biomolecular characterization unit, Center for Sustainable Resource Science, RIKEN (2)
Cellular Neurophysiology, Center for Integrative Physiology and Molecular Medicine (CIPMM), Saarland University, 66421 Homburg, Germany (2)
Head of Cell Signaling and Clinical Proteomics Group. IIS Biobizkaia. Ikerbasque. (2)
Laboratory of Mass Spectrometry, Core Facility Laboratories, Intercollegiate Faculty of Biotechnology UG&MUG, University of Gdansk, Gdansk, Poland (2)
Shanghai Jiao Tong University Affiliated Sixth People's Hospital (2)
1)Department of Pediatrics III, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany. 2)Department of General, Visceral, Vascular and Transplant Surgery, Medical Faculty, University Hospital Essen, Hufelandstrasse 55, 45147 Essen, Germany. (1)
1State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, School of Medicine, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing 210096, China.2 Co-Innovation Center of Neuroregeneration, Nantong University, Nantong 226001, China. (1)
Associate Professor (1)
Baker Heart & Diabetes Inst. (1)
Baker Heart and Diabetes Institute (1)
Bavarian Center for Biomolecular Mass Spectrometry at Klinikum rechts der Isar (BayBioMS@MRI), TUM School of Medicine and Health, Technical University of Munich (TUM), 81675 München, Germany (1)
Bioeconomy Science Institute, AgResearch Ltd., Lincoln 7674, New Zealand. (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands; Netherlands Proteomics Centre, Padualaan 8, 3584 CH Utrecht, The Netherlands; and Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. (1)
Brain Tumor Translational Targets B067 German Cancer Research Center (DKFZ) Im Neuenheimer Feld 580 69120 Heidelberg Germany Phone: +49 6221 42-4635 (1)
Cell Culture Technology, Technical Faculty, Bielefeld University, Germany (1)
Cellular & Molecular Metabolism Laboratory, Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University. (1)
Chronic Disease Programme (UFIEC), Instituto de Salud Carlos III, Majadahonda, E-28220 Madrid, Spain (1)
Chronic Disease Programme (UFIEC), Instituto de Salud Carlos III, Majadahonda, Madrid, Spain (1)
Chronic Disease Programme, UFIEC, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain (1)
Computational and Experimental Biology Group NOVA MEDICAL SCHOOL / FACULDADE DE CIÊNCIAS MÉDICAS UNIVERSIDADE NOVA DE LISBOA Rua Câmara Pestana, 6-6A | 1150-082 Lisboa Portugal (1)
Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Paraná, PR, Brasil. Instituto Oswaldo Cruz, Rio de Janeiro, Brasil (1)
Department of Biophysics, All India Institute of Medical Sciences, New Delhi, Delhi, India (110029) (1)
Department of Biotechnology, TU Delft, NL (1)
Department of Chemistry and Biomolecular Sciences, University of Ottawa, Canada (lab head) (1)
Department of Clinical Laboratory, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University (1)
Department of Experimental Pathology, Institut d’Investigacions Biomèdiques de Barcelona, Consejo Superior de Investigaciones Científicas (IIBB-CSIC), Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. (1)
Department of Immunology, Genetics & Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden. (1)
Department of Medicine and Animal Surgery, Faculty of Veterinary Science, University of Murcia, Murcia, Spain (1)

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Characterization of small intracellular vesicles uncovers their potential as drug carriers and therapeutic agents

Small extracellular vesicles (sEVs) have been extensively investigated as a source of clinically relevant cargo. Alongside the secretion of EVs, such as exosomes, cells house a multitude of internal vesicles involved in various physiologic processes and metabolic activities. Herein, we developed ...

2025-09-02 | MTBLS12923 | MetaboLights

Small RNA-Seq for primary rat hepatic stellate cells and hepatic stellate cell-derived small extracellular vesicles

Aims: To obtain small non-coding RNA expression profiles of short-term activated and long-term activated hepatic stellate cells (HSCs). To obtain small non-coding RNA expression profiles of small extracellular vesicles (sEVs) from short-term activated and long-term activated HSCs. Methods: Primar...

ORGANISM(S): Rattus norvegicus

2024-08-29 | E-MTAB-12764 | biostudies-arrayexpress

Acute and chronic liver injury change the small RNA cargoes carried by serum small extracellular vesicles in mice

Compared to whole serum miRNAs, miRNAs in serum small extracellular vesicles (sEVs) are well protected form RNA enzymes, thus provide a consistent source of miRNA for disease biomarker detection. Serum sEVs and their miRNA cargos released by injured liver cells could be promising biomarkers for diag...

ORGANISM(S): Mus musculus

2021-08-07 | E-MTAB-9462 | biostudies-arrayexpress

RNA-Seq for primary rat Kupffer cells and monocytes treated with hepatic stellate cell-derived small extracellular vesicles

Aim: To find out the effects of small extracellular vesicles (sEVs) from short-term activated and long-term activated hepatic stellate cells (HSCs) on Kupffer cells (KCs) and bone marrow-derived monocytes (MOs). Methods: For the isolation of HSC-derived sEVs, culture media (CMs) from Day 0 to Day 3 ...

ORGANISM(S): Rattus norvegicus

2024-08-29 | E-MTAB-12754 | biostudies-arrayexpress

Proteomic, phosphoproteomic and N-glycoproteomic analysis of small extracellular vesicles (sEVs) from C2C12 myoblasts

We conducted a comprehensive and integrated proteomic，phosphoproteomic, N-glycoproteomic analysis of the cargos in small extracellular vesicles (sEVs)-derived from C2C12 myoblasts.

ORGANISM(S): Mus Musculus

2023-12-20 | PXD047974 |

LC-MS of small extracellular vesicles (sEVs) secreted by mock- vs. Zika virus (ZIKV)-infected JEG-3 cells

Proteomics profiling of small extracellular vesicles secreted by mock- vs. ZIKV (PRVABC59)-infected JEG-3 cells.

ORGANISM(S): Homo sapiens (Human)

2023-09-12 | PXD041807 | Pride

Mouse osteoclast-small extracellular vesicles LC-MSMS

Small extracellular vesicles secreted from maturing osteoclasts were collected and analyzed for identifying their protein components

ORGANISM(S): Mus musculus (Mouse)

2018-09-06 | PXD010500 | Pride

Lc-msms Mouse Osteoclast Small extracellular vesicles

Real-time monitoring of small extracellular vesicles (sEVs) by in vivo flow cytometry.

Not available

S-EPMC11497658 | biostudies-literature

Proteomic profiling of glioblastoma stem cells and their small extracellular vesicles

The heterogeneous nature of glioblastoma stem-like cells (GSCs) creates hurdles in developing effective therapies against glioblastoma, making it extremely difficult to eradicate. In this part of the project, we investigated the potential role of GSCs-derived small extracellular vesicles (sEVs) in g...

ORGANISM(S): Homo sapiens (Human)

2024-05-21 | PXD036359 | Pride

Glioblastoma Glioblastoma stem cells Exosomes Tumor heterogeneity Proteomics Small extracellular vesicles

Running title: Highly pure isolation of small extracellular vesicles from bovine plasma Title: Technical note: Efficient enrichment of plasma-derived extracellular vesicles from small volumes of bovine blood

This study presents a scalable method for isolating small extracellular vesicles (sEVs) according to MISEV (minimal information for studies of extracellular vesicles) guidelines from 4 mL of bovine plasma while achieving a high purity suitable for proteomics analysis. The protocol combines ultracent...

ORGANISM(S): Bos taurus (Bovine)

2025-11-17 | PXD068315 | Pride

Biomarker discovery Methodology optimization Phenotypic expressions Proteomics Vesicle-associated proteins Lipoprotein removal

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1161 Results

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