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ProteomicsImproved Identification and Analysis of Small Open Reading Frame Encoded Polypeptides
Computational, genomic, and proteomic approaches have been used to discover nonannotated proteincoding small open reading frames (smORFs). Some novel smORFs have crucial biological roles in cells and organisms, which motivates the search for additional smORFs. Proteomic smORF discovery methods are a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-26 | MSV000084014 | MassIVE
ProteomicsUpstream ORF-encoded ASDURF is a novel prefoldin-like subunit of the PAQosome
The PAQosome is an eleven-subunit chaperone involved in the biogenesis of several human protein complexes. We show that ASDURF, a recently discovered upstream open reading frame (uORF) in the 5’ UTR of ASNSD1 mRNA, encodes the twelfth subunit of the PAQosome. ASDURF, displays significant structural ...
ORGANISM(S): Homo sapiens (Human) 
2019-11-25 | PXD015848 | Pride
Ap-ms Protein complex assembly Uorf Paqosome Small orf encoded peptide Chaperone Asdurf Bioid R2tp/pfdl Prefoldin 
TranscriptomicsIdentification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation
Identification of the coding elements in the genome is a fundamental step to understanding the building blocks of living systems. Short peptides (< 100 aa) have emerged as important regulators of development and physiology, but their identification has been limited by their size. We have leveraged t...
ORGANISM(S): Danio rerio 
2014-04-04 | E-GEOD-53693 | biostudies-arrayexpress
TranscriptomicsSmall RNA deep-sequencing identifies microRNAs and other small non-coding RNAs from human herpesvirus 6 (HHV-6B)
Roseolovirus, or human herpesvirus 6 (HHV-6) is a ubiquitous human pathogen infecting over 95% of the population by the age of two years. As with other herpesviruses, reactivation of HHV-6 can present with severe complications in immunocompromised individuals. Recent studies have highlighted the imp...
ORGANISM(S): Human herpesvirus 6B 
2012-01-01 | E-GEOD-34196 | biostudies-arrayexpress
Genomics
LncRNA-encoded small peptide promotes viral infection
PRJNA1199045 | ENA
ProteomicsHidden in plain sight; challenges in proteomics detection of small ORF-encoded polypeptides.
Genomic studies of bacteria have long pointed towards widespread prevalence of small open reading frames (sORFs) encoding for short proteins, less than 100 amino acids in length. Despite the mounting genomic evidence of their robust expression, little progress has been made in their mass spectrometr...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2023-07-20 | PXD029391 | Pride
Salmonella Peptidomics Seps 
ProteomicsAn Optimised Proteomics Workflow for the Detection of Small Proteins.
Small open reading frame encoded proteins (SEPs) gained increasing interest during the last years due to their broad range of important functions in both, prokaryotes and eukaryotes. In bacteria, signalling, virulence or regulation of enzyme activities have been associated with SEPs. Nonetheless, th...
ORGANISM(S): Bacillus Subtilis 
2020-09-08 | PXD020514 | panorama
ProteomicsIdentification interactional proteins related with KDM4A-AS1-encoded peptides in HEK293T
This study was conducted by using Flag tag to IP proteins expressed with fusion small peptides encoding KDM4A-AS1 and identified by high resolution mass spectrometry.
ORGANISM(S): Homo Sapiens 
2022-11-14 | PXD038125 |
ProteomicsIdentification of small open reading frame encoded peptides of Thermosynechococcus vestitus BP-1(2133)
Identification of small open reading frame encoded peptides of Thermosynechococcus vestitus BP-1(2133)
ORGANISM(S): Thermosynechococcus Elongatus Bp-1 
2025-01-09 | PXD059620 |
ProteomicsIdentification of small open reading frame encoded peptides of Synechocystis sp. PCC 6803 (6803)
Identification of small open reading frame encoded peptides of Synechocystis sp. PCC 6803 (6803)
ORGANISM(S): Synechocystis Sp. Pcc 6803 Substr. Kazusa 
2025-01-08 | PXD059576 |
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