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ChIP-seq data of prefoldin subunit PFDN5 in HCT116 human colon carcinoma cells
The PAQosome is an eleven-subunit chaperone involved in the biogenesis of several human protein complexes. We show that ASDURF, a recently discovered upstream open reading frame (uORF) in the 5’ UTR of ASNSD1 mRNA, encodes the twelfth subunit of the PAQosome. ASDURF, displays significant structural ...
ORGANISM(S): Homo sapiens (Human) 
2019-11-25 | PXD015848 | Pride
Prefoldin is a heterohexameric complex conserved from archaea to humans that plays a cochaperone role during the co-translational folding of actin and tubulin monomers. Additional functions of prefoldin in the cell nucleus have been described, including a positive contribution to transcription elong...
ORGANISM(S): Homo sapiens 
2021-05-04 | GSE171466 | GEO
The goal of this study was to identify yeast mutants with arsenite hypersensitivity. Keywords: dose response Matched pools of yeast knockout (YKO) mutants were grown in paired growth media lacking or containing arsenite at various concentrations. The relative abundances of the YKO mutants were profi...
ORGANISM(S): Saccharomyces cerevisiae 
RNAseq in Arabidopsis prefoldin mutants
We analyzed consequences of the loss of prefoldin subunits on the cell proliferation and survival of Saccharomyces cerevisiae upon exposure to various cellular stress conditions. Mass spectrometry analysis comparing whole yeast proteomes of cells lacking PFD2 versus wild type cells was performed. We...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-09-13 | PXD040390 | Pride
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