Sort   by:  
 Page size 
ProteomicsImproved Identification and Analysis of Small Open Reading Frame Encoded Polypeptides
Computational, genomic, and proteomic approaches have been used to discover nonannotated proteincoding small open reading frames (smORFs). Some novel smORFs have crucial biological roles in cells and organisms, which motivates the search for additional smORFs. Proteomic smORF discovery methods are a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-26 | MSV000084014 | MassIVE
ProteomicsUpstream ORF-encoded ASDURF is a novel prefoldin-like subunit of the PAQosome
The PAQosome is an eleven-subunit chaperone involved in the biogenesis of several human protein complexes. We show that ASDURF, a recently discovered upstream open reading frame (uORF) in the 5’ UTR of ASNSD1 mRNA, encodes the twelfth subunit of the PAQosome. ASDURF, displays significant structural ...
ORGANISM(S): Homo sapiens (Human) 
2019-11-25 | PXD015848 | Pride
Ap-ms Protein complex assembly Uorf Paqosome Small orf encoded peptide Chaperone Asdurf Bioid R2tp/pfdl Prefoldin 
ProteomicsAn Optimised Proteomics Workflow for the Detection of Small Proteins.
Small open reading frame encoded proteins (SEPs) gained increasing interest during the last years due to their broad range of important functions in both, prokaryotes and eukaryotes. In bacteria, signalling, virulence or regulation of enzyme activities have been associated with SEPs. Nonetheless, th...
ORGANISM(S): Bacillus Subtilis 
2020-09-08 | PXD020514 | panorama
UnknownIdentification of small ORF-encoded peptides in mouse serum.
Not available
S-EPMC5860097 | biostudies-literature
ProteomicsSmall ORF16 modulates the Mtr complex activity in Methanosarcina mazei depending on the molecular hydrogen availability
Small open reading frame (small ORF)-encoded proteins, with less than 100 amino acids in length, have attracted increasing attention over the past decade after being largely overlooked due to limitations in classical bioinformatics and biochemical methodologies. For the mesophilic archaeal model sys...
ORGANISM(S): Methanosarcina mazei Go1 
2026-09-07 | PXD064332 | Pride
Tetrahydrosarcinapterin s-methyltransferase (mtr) Small orf encoded proteins Methanosarcina mazei Lc msms 
ProteomicsHidden in plain sight; challenges in proteomics detection of small ORF-encoded polypeptides.
Genomic studies of bacteria have long pointed towards widespread prevalence of small open reading frames (sORFs) encoding for short proteins, less than 100 amino acids in length. Despite the mounting genomic evidence of their robust expression, little progress has been made in their mass spectrometr...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2023-07-20 | PXD029391 | Pride
Salmonella Peptidomics Seps 
TranscriptomicsSmall RNA deep-sequencing identifies microRNAs and other small non-coding RNAs from human herpesvirus 6 (HHV-6B)
Roseolovirus, or human herpesvirus 6 (HHV-6) is a ubiquitous human pathogen infecting over 95% of the population by the age of two years. As with other herpesviruses, reactivation of HHV-6 can present with severe complications in immunocompromised individuals. Recent studies have highlighted the imp...
ORGANISM(S): Human herpesvirus 6B 
2012-01-01 | E-GEOD-34196 | biostudies-arrayexpress
TranscriptomicsTranscriptional perturbations caused by tumor virus proteins
Genotypic differences greatly influence susceptibility and resistance to disease. Understanding genotype-phenotype relationships requires that phenotypes be viewed as manifestations of network properties, rather than simply as the result of individual genomic variations. Genome sequencing efforts ha...
ORGANISM(S): Homo sapiens 
2012-07-19 | E-GEOD-38467 | biostudies-arrayexpress
TranscriptomicsIdentification of RNAs that are physically and functionally associated with RNase P
Numerous RNAs copurify with RNase P and are affected by temperture sensitive mutations in conserved residues with the essential RNA and protein subunits. Specifically, RNase P physically interacts with ribosomal protein mRNAS and the intron-encoded box C/D snoRNAs. Keywords: RNA copurification, tem...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-01 | E-GEOD-10514 | biostudies-arrayexpress
UnknownThe small protein LINC01547-ORF inhibits colorectal cancer progression by regulating the CLDN18-FAK-AKT axis.
Not available
S-EPMC11626262 | biostudies-literature
Sort   by:  
 Page size