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TranscriptomicsThe ISWI ATPase Snf2L is required for superovulation and regulates Fgl2 in differentiating mouse granulosa cells
We investigate the role of Snf2l in ovaries by characterizing a mouse bearing an inactivating deletion on the ATPase domain of Snf2l (Ex6DEL). Snf2l mutant mice produce significantly fewer eggs than control mice when superovulated. Thus, gonadotropin stimulation leads to a significant deficit in sec...
ORGANISM(S): Mus musculus 
2013-05-01 | E-GEOD-42997 | biostudies-arrayexpress
TranscriptomicsThe nucleosome remodeler SNF2L modulates WNT signaling for cellular homeostasis
ISWI is an evolutionary conserved ATPase that catalyzes nucleosome remodeling in several different complexes. Two mammalian ISWI orthologs, SNF2H and SNF2L, have specialized functions despite their high similarity. Due to the lack of reagents the functions of SN2L in human cells had not been establi...
ORGANISM(S): Homo sapiens 
2012-05-10 | E-GEOD-30471 | biostudies-arrayexpress
ProteomicsRegulation of the developmental programs in Toxoplasma by a novel SNF2L-containing chromatin remodeling complex
Regulation of the developmental programs in Toxoplasma by a novel SNF2L-containing chromatin remodeling complex
ORGANISM(S): Toxoplasma gondii Toxoplasma gondii ME49 
2025-05-23 | PXD055403 | Pride
Toxoplasma Snf2l 
TranscriptomicsMouse E15.5 cortices: Snf2l Ex6 deleted mice versus wild type controls
Gene expression profiling of mouse cortices in which the experimental strain lacks Exon 6 of the Snf2l gene which encodes an ATP-binding motif that is critical for chromatin re-modeling Comparison of gene expression in E15.5 cortices of Snf2l-Ex6DEL mice versus wild type controls. Two samples of eac...
ORGANISM(S): Mus musculus 
2012-04-09 | E-GEOD-34998 | biostudies-arrayexpress
ProteomicsIdentification of differentially expressed proteins in SNF2L-deficient MDA-MB-231 cells using mass spectrometry.
To identify SNF2L target proteins involved in GSH homeostasis in cancer cells, we conducted a quantitative proteomic screening of SNF2L-KO and parental MDA-MB-231 cells.
ORGANISM(S): Homo sapiens (Human) 
2024-11-12 | PXD052912 | Pride
Snf2l-ko Ms Mda-mb-231 cell 
UnknownSNF2L suppresses nascent DNA gap formation to promote DNA synthesis.
Not available
S-EPMC11602140 | biostudies-literature
UnknownSNF2L maintains glutathione homeostasis by initiating SLC7A11 transcription through chromatin remodeling.
Not available
S-EPMC11557580 | biostudies-literature
UnknownNucleosome remodeler SNF2L suppresses cell proliferation and migration and attenuates Wnt signaling.
Not available
S-EPMC3434487 | biostudies-literature
GenomicsThe Chromatin Remodelling Contributions of Snf2l in Cerebellar Granule Neuron Differentiation [RNA-Seq]
The Chromatin Remodelling Contributions of Snf2l in Cerebellar Granule Neuron Differentiation [RNA-Seq]
PRJNA503868 | ENA
GenomicsThe Chromatin Remodelling Contributions of Snf2l in Cerebellar Granule Neuron Differentiation [ATAC-Seq]
The Chromatin Remodelling Contributions of Snf2l in Cerebellar Granule Neuron Differentiation [ATAC-Seq]
PRJNA503869 | ENA
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