Sort   by:  
 Page size 
TranscriptomicsIdentification of transcriptome SNPs for assessing allele specific gene expression within a super-hybrid rice Xieyou9308
We identified 9325 reliable single nucleotide polymorphisms (SNPs) distributed throughout the genome, of which nearly 68% were represented in R9308 versus Xieqingzao B by CT and GA SNPs. This may indicate that DNA methylation, a heritable epigenetic mark, exists in the parents and their F1 hybrid. O...
ORGANISM(S): Oryza sativa 
2014-05-16 | E-GEOD-43727 | biostudies-arrayexpress
GenomicsSNPs in Ormosia boluoensis
SNPs in Ormosia boluoensis
PRJEB123022 | ENA
ProteomicsHigh-throughput identification of functional regulatory SNPs in systemic lupus erythematosus
Genome-wide association studies implicate multiple loci in risk for systemic lupus erythematosus (SLE), but few contain exonic variants, rendering systematic identification of non-coding variants essential to decoding SLE genetics. We utilized SNP-seq and bioinformatic enrichment to interrogate 2180...
ORGANISM(S): Homo sapiens (Human) 
2024-08-02 | PXD048367 | Pride
Lc-msms Human B cell Sle 
TranscriptomicsAllelic expression mapping across cell lineages reveal repressor disruption among disease SNPs
Most variants associated to diseases are located in non-coding regions of the genome, and are thought to be regulatory in nature. Cis-regulatory SNPs (cis-rSNPs) impacting transcription can be identified through the mapping of differences in allelic expression (AE). We mapped common cis-rSNPs of pro...
ORGANISM(S): Homo sapiens 
2014-11-03 | E-GEOD-53837 | biostudies-arrayexpress
TranscriptomicsCoronary artery disease-associated genotype data in Mediterranean populations
We wanted to explore the genomic regions 1p13, 1q41, 9p21 and 10q11, which are among the labeled “top 12 golden loci” linked to coronary artery disease (CAD) risk, in order to see whether their geographic variation could be explained by demographic effects. To do this, we have genotyped these ri...
ORGANISM(S): Homo sapiens 
2016-11-24 | E-MTAB-5265 | biostudies-arrayexpress
GenomicsDeciphering Regulatory SNPs from ATAC-seq
Deciphering Regulatory SNPs from ATAC-seq
PRJNA606502 | ENA
TranscriptomicsTranscriptome sequencing of Eucalyptus camaldulensis seedlings subjected to water stress reveals functional single nucleotide polymorphisms and genes under selection.
Purpose: Water stress limits plant survival and production in many parts of the world. Identification of genes and alleles responding to water stress conditions is important in breeding plants better adapted to drought. Currently there are no studies examining the transcriptome wide gene and allelic...
ORGANISM(S): Eucalyptus camaldulensis 
2012-07-17 | E-GEOD-39369 | biostudies-arrayexpress
ProteomicsBreast cancer risk SNPs converge on estrogen receptor binding sites commonly shared between breast tumors to locally alter estrogen signalling output
Estrogen Receptor alpha (ERa) is the main driver of luminal breast cancer development and progression, and represents the main drug target in patient care. ERa chromatin binding has been extensively studied in breast cancer cell lines and a number of human tumors, often focused on differential bindi...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD045526 | Pride
Breast cancer Estrogen receptor Enhancers Snps Rs9952980 
GenomicsFunctional Significance of Prostate Cancer risk-SNPs
Functional Significance of Prostate Cancer risk-SNPs
PRJNA294704 | ENA
TranscriptomicsCandidate SNPs association with APOC3
ApoC-III is a proatherogenic protein associated with elevated triglycerides; its deficiency is associated with reduced atherosclerosis. Mixed dyslipidemia, characterized by elevated triglyceride and apoC-III levels and low HDL cholesterol level, with or without elevated LDL cholesterol, increases ca...
ORGANISM(S): Homo sapiens 
2012-01-11 | E-GEOD-34945 | biostudies-arrayexpress
Sort   by:  
 Page size