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ProteomicsCullin 3 Mouse Brain TMT-based Proteomics Analysis
This project consists in 3 datasets: - Samples from adult mouse brains (Hippocampus, Cortex and Cerebellum): Cul3 +/- or +/+; 5 animals per condition. - Samples from embryonic mouse cortex: either Cul3 +/- or +/+ - Samples from embryonic mouse cortex: Cul3 fl/fl Emx-1-Cre ("hom"); Cul3 +/fl Emx1-Cre...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-26 | PXD017040 | Pride
Mouse brain cullin 3 cul3 autism cortex cerebellum hippocampus embryonic adult tmt dda high ph rp 
ProteomicsCdk5r1_KO_TMT-10plex_brain_cell-autonomous_proteomics
Concerted radial migration of newly born cortical projection neurons, from their birthplace to their final target lamina, is a key step in the assembly of the cerebral cortex. The cellular and molecular mechanisms regulating radial neuronal migration in vivo are however still unclear, let alone the ...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-22 | PXD023222 | Pride
Mus musculus Brain Facs sorted 
ProteomicsLight-triggered and phosphorylation-dependent 14-3-3 association with NON-PHOTOTROPIC HYPOCOTYL 3 is required for hypocotyl phototropism
NON-PHOTOTROPIC HYPOCOTYL 3 (NPH3) is a key component of the auxin-dependent plant phototropic growth response. We report that NPH3 directly binds polyacidic phospholipids, required for plasma membrane association in darkness. We further demonstrate that blue light induces an immediate phosphorylati...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-10-12 | PXD028530 | Pride
Arabidopsis thaliana Etiolated seedling Blue-light dependent 14-3-3 interactors 
TranscriptomicsEffect of hepatocyte-restricted deletion of fgf21 deletion on liver gene expression in response to fasting in mice
FGF21 is a liver-derived hormone potently induced in response to fasting. However, its role in the regulation of hepatic gene expression is unknown. The effect of 20h fasting on liver gene expression was investigated in wild-type mice and in mice lacking hepatocyte FGF21. Fgf21 hepatocyte-specific ...
ORGANISM(S): Mus musculus 
2026-10-16 | E-MTAB-15848 | biostudies-arrayexpress
TranscriptomicsEffect of hepatocyte FGF21 on brown adipose tissue gene expression in mice
FGF21 is an hepatokine, a liver-derived hormone, that is highly induced and secreted in response to fasting. We investigated the role of hepatic FGF21 on gene expression profile in the brown adipose tissue. The effect of 20h fasting on brown adipose tissue gene expression was investigated in male wi...
ORGANISM(S): Mus musculus 
2026-10-17 | E-MTAB-15855 | biostudies-arrayexpress
TranscriptomicsEffect of hepatocyte-restricted deletion of fgf21 deletion on perigonadic white adipose tissue gene expression in response to fasting in mice
FGF21 is a liver-derived hormone. It is potently induced and secreted in response to fasting. However, the biological significance of this endocrine response remains poorly understood. Here, we investigated the effect of hepatocyte FGF21 on perigonadic white adipose tissue biology through the analys...
ORGANISM(S): Mus musculus 
2026-10-20 | E-MTAB-15878 | biostudies-arrayexpress
TranscriptomicsEffect of hepatocyte-restricted deletion of FGF21 on subcutaneous white adipose tissue gene expression in fasting mice
FGF21 is a liver-derived hormone. FGF21 expression and secretion from hepatocytes is potently induced in response to fasting. However, the significance of such fasting-induced hepatokine production is poorly understood. Here, we investigated the putative effect of hepatocyte-derived FGF21 on fasting...
ORGANISM(S): Mus musculus 
2026-10-20 | E-MTAB-15880 | biostudies-arrayexpress
UnknownEffect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study.
Not available
S-EPMC8492020 | biostudies-literature
UnknownTwo phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Not available
S-EPMC4159618 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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