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ProteomicsProteome characterization of HCMV virus microenvironment
The control of host processes which influence cell-cell communication is central to determining the outcome of a virus infection in tissue. Despite this, it remains unclear how cells either in close or distant proximity to an infected cell differentially respond to the primary infection. Here, we es...
ORGANISM(S): Homo sapiens (Human) Human betaherpesvirus 5 
2023-05-11 | PXD038547 | Pride
Hcmv Innate immunity Membrane contact sites Mass spectrometry Virus microenvironment Cell cycle Susceptibility 
ProteomicsProteome characterization of HCMV virus microenvironment with addition of cidofovir
The control of host processes which influence cell-cell communication is central to determining the outcome of a virus infection in tissue. Despite this, it remains unclear how cells either in close or distant proximity to an infected cell differentially respond to the primary infection. Here, we es...
ORGANISM(S): Homo sapiens (Human) 
2023-05-11 | PXD040582 | Pride
Hcmv Innate immunity Membrane contact sites Mass spectrometry Virus microenvironment Cell cycle Cidofovir 
ProteomicsPRM quantification of MCS proteins and viral proteins in HCMV virus microenvironment
The control of host processes which influence cell-cell communication is central to determining the outcome of a virus infection in tissue. Despite this, it remains unclear how cells either in close or distant proximity to an infected cell differentially respond to the primary infection. We establis...
ORGANISM(S): Homo Sapiens Human Betaherpesvirus 5 
PXD038466 | panorama
ProteomicsIdentification of cGAS post-translational modifications
DNA derived from the genetic material of pathogens or from cellular DNA damage provides a molecular pattern that can be sensed by pattern-recognition receptors of the mammalian innate immune system. In recent years, the cyclic GMP-AMP synthase (cGAS) protein has been characterized as a primary cytos...
ORGANISM(S): Homo Sapiens 
2020-05-08 | PXD017133 | panorama
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