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ProteomicsProteomic and phosphoproteomic study in the retina, choroid, and sclera of guinea pigs with form-deprivation myopia
Myopia is a growing global public health concern. Recent studies have revealed that the regulation of eye growth occurs via a complex signaling cascade, which originates in the retina and across the choroid to the sclera. Identifying key proteins and specific biological processes in the retina, chor...
ORGANISM(S): Cavia porcellus (Guinea pig) 
2025-11-17 | PXD067756 | Pride
Retina Choroid Form-deprivation myopia Sclera Proteomics and phosphoproteomics 
ProteomicsProteomic and phosphoproteomic study in the retina, choroid, and sclera of guinea pigs with form-deprivation myopia
Myopia is a growing global public health concern. Recent studies have revealed that the regulation of eye growth occurs via a complex signaling cascade, which originates in the retina and across the choroid to the sclera. Identifying key proteins and specific biological processes in the retina, chor...
ORGANISM(S): Cavia porcellus (Guinea pig) 
2025-11-17 | PXD067757 | Pride
Retina Choroid Form-deprivation myopia Sclera Proteomics and phosphoproteomics 
ProteomicsProteomic and phosphoproteomic study in the retina, choroid, and sclera of guinea pigs with form-deprivation myopia
Myopia is a growing global public health concern. Recent studies have revealed that the regulation of eye growth occurs via a complex signaling cascade, which originates in the retina and across the choroid to the sclera. Identifying key proteins and specific biological processes in the retina, chor...
ORGANISM(S): Cavia porcellus (Guinea pig) 
2025-11-17 | PXD067446 | Pride
Retina Choroid Form-deprivation myopia Sclera Proteomics and phosphoproteomics 
ProteomicsProteomic and phosphoproteomic study in the retina, choroid, and sclera of guinea pigs with form-deprivation myopia
Myopia is a growing global public health concern. The retinal–choroid–sclera (RCS) signalling cascade is crucial in regulating eye growth and is influenced by visually induced signalling. Understanding the molecular mechanisms underlying this cascade is vital to identify therapeutic targets for myop...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-17 | PXD052167 | Pride
Phosphoproteomic Proteomic Form-deprivation myopia (fdm)  retina-choroid-sclera (rcs) 
ProteomicsLactylome analysis reveals potential target modified proteins in the retina of form-deprivation myopia
Myopia has become the major cause of visual impairment worldwide. Although the pathogenesis of myopia remains controversial, proteomics studies suggest that dysregulation of retinal metabolism is potentially involved in the pathology of myopia. Lysine lactylation of proteins plays a key role in regu...
ORGANISM(S): Cavia porcellus (Guinea pig) 
2024-10-17 | PXD046495 | Pride
Lysine lactylation Form-deprivation myopia Lactate Aerobic glycolysis Retina 
ProteomicsProteomic profiling of muscular adaptations to short-term concentric vs. eccentric exercise training in humans
The study used liquid-chromatography tandem mass spectrometry (LC-MS/MS) combined with bioinformatics analysis to analyze muscle biopsies from the vastus lateralis muscles obtained from two groups of young males after four weeks of either concentric or eccentric resistance training of the quadriceps...
ORGANISM(S): Homo Sapiens 
2023-12-17 | PXD047890 |
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