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ProteomicsPanoramix SUMOylation at chromatin recruits the heterochromatin machinery to piRNA target loci
Nuclear Argonaute proteins, guided by small RNAs, mediate sequence-specific heterochromatin formation. The molecular principles that link Argonaute–small RNA complexes, once bound to a nascent target RNA, to general heterochromatin effectors are poorly understood. Here, we uncover the mechanistic ba...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-05-06 | PXD025437 | Pride
Panx Sov Drosophila Pirna Heterochromatin Sumo Lxxll 
GenomicsTranscriptional profiles of sov mutant ovaries
Transcriptional profiles of sov mutant ovaries
PRJNA454717 | ENA
TranscriptomicsTranscriptional profiles of sov mutant ovaries
Stranded, single-end, polyA+, transcriptional profiles were created from ovaries of sterile and fertile sov heteroallelic mutants and Gal4 driven sov RNAi knockdowns.
ORGANISM(S): Drosophila melanogaster 
2019-01-01 | GSE113977 | GEO
GenomicsSov is required for genome-wide H3K9me3 deposition in Drosophila germ cells
Sov is required for genome-wide H3K9me3 deposition in Drosophila germ cells
PRJNA515036 | ENA
TranscriptomicsTranscription profiling of human lung fibroblasts (HLF) treated with Cr(VI) a carcingogen in the presence of PTP to investigate the effect of protein tyrosine phosphatases inhibition on changes in gene expression
Although the consequences of genotoxic injury include cell cycle arrest and apoptosis, cell survival responses after genotoxic injury can produce intrinsic death-resistance and contribute to the development of a transformed phenotype. Protein tyrosine phosphatases (PTPs) are integral components of k...
ORGANISM(S): Homo sapiens 
2009-01-13 | E-GEOD-12205 | biostudies-arrayexpress
GenomicsSov is required for genome-wide H3K9me3 deposition in Drosophila germ cells
Sov was recently shown to play a role in heterochromatin formation in the Drosophila ovary. Here, we explored the effect of germline knockdown of Sov on the genome-wide levels of H3K9me3 by ChIP-seq
ORGANISM(S): Drosophila melanogaster 
2019-09-01 | GSE125055 | GEO
Genomics
DNA sequencing analysis of sov alleles
PRJNA454692 | ENA
UnknownProtein Interactome Analysis of the Type IX Secretion System Identifies PorW as the Missing Link between the PorK/N Ring Complex and the Sov Translocon.
Not available
S-EPMC8754138 | biostudies-literature
UnknownMapping of two suppressors of OVATE (sov) loci in tomato.
Not available
S-EPMC3746822 | biostudies-literature
GenomicsThe Cytoplasmic mRNA Decay Landscape of Arabidopsis Seedlings [small RNA-seq]
Cytoplasmic mRNA decay occurs through several pathways, but the contributions of these decay pathways to the degradation of specific mRNAs, and interactions between the pathways, are not well understood. We carried out a genome-wide analysis of mRNA decay rates using wild-type Arabidopsis and mutant...
ORGANISM(S): Arabidopsis thaliana 
2018-01-26 | GSE86360 | GEO
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