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ProteomicsAn optimized version of the Secretome protein enrichment with click sugars (SPECS) method leads to enhanced coverage of the secretome
The secretome, the entirety of all soluble proteins either being secreted or proteolytically released by a cell, plays a key role in intercellular communication of multicellular organisms. Pathological alterations contribute to diseases such as hypertension, cancer, autoimmune disorders or neurodege...
ORGANISM(S): Homo sapiens (Human) 
2017-11-24 | PXD004555 | Pride
Glycocapture Glycoprotein Label-free quantification Specs 
UnknownSPECS: a non-parametric method to identify tissue-specific molecular features for unbalanced sample groups.
Not available
S-EPMC7026976 | biostudies-literature
UnknownSPECS: Integration of side-chain orientation and global distance-based measures for improved evaluation of protein structural models.
Not available
S-EPMC7018003 | biostudies-literature
ProteomicsSPECS and proteomics analysis of secreted glycosylated proteins regulated by ADAM12S
We used the secretome protein enrichment with click sugars (SPECS) method to purify the secreted glycosylated proteins and performed quantitative proteomics to identify the secreted proteins that were regulated by ADAM12S.
ORGANISM(S): Homo Sapiens 
2022-02-06 | PXD031470 |
ProteomicsSPPL3 cleavage of glycosyltransferases regulates their activity
The GxGD intramembrane-cleaving aspartylprotease signal peptide peptidase-like 3 (SPPL3) is a Golgi-resident, multi-pass membrane protein that is highly conserved among multicellular eukaryotes pointing to a pivotal physiological function in the Golgi network. Recently, the key branching enzyme N-ac...
ORGANISM(S): Homo sapiens (Human) 
2015-05-08 | PXD001672 | Pride
Substrates Protease Specs Sppl3 
UnknownLongitudinal pre-exposure prophylaxis (PrEP) acceptability, initiation and adherence among criminal justice-involved adults in the USA: the Southern PrEP Cohort Study (SPECS) protocol.
Not available
S-EPMC8287623 | biostudies-literature
UnknownEarly growth response 3 (Egr3) is highly over-expressed in non-relapsing prostate cancer but not in relapsing prostate cancer.
Not available
S-EPMC3544741 | biostudies-literature
UnknownEssential requirements for the governance and management of data trusts, data repositories, and other data collaborations.
Not available
S-EPMC10898504 | biostudies-literature
UnknownVascular Tissue Engineering Using Scaffold-Free Prevascular Endothelial-Fibroblast Constructs.
Not available
S-EPMC6327854 | biostudies-literature
UnknownComparison of serratus plane block alone and in combination with pectoral type 1 block for breast cancer surgery: a randomized controlled study.
Not available
S-EPMC8877920 | biostudies-literature
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