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MetabolomicsNGT induced mitochondrial dysfunction, led to apoptosis, and changed metabolites associated with oxidized lipids in sperm of Pacific oyster (Crassostrea gigas).

The risk of norgestrel (NGT) exposure in the aquatic environment has been identified, but the toxic effects on invertebrate germ cells are unknown. Therefore, the toxic effects of NGT on oyster sperm were investigated by combining transcriptome and metabolome analysis with histology. Transcriptom...

2025-07-05 | MTBLS12685 | MetaboLights
TranscriptomicsStallion sperm transcriptome as revealed by microarray analysis and RNA sequencing
Purpose: In order to understand the functional significance of sperm transcriptome in stallion fertility, the aim of this study was to generate a detailed body of knowledge about the sperm RNA profile that defines a normal fertile stallion. Methods: The 50 bp single-end ABI SOLiD raw reads were dire...
ORGANISM(S): Equus caballus 
2013-02-19 | E-GEOD-38725 | biostudies-arrayexpress
ProteomicsMouse Sperm TMT MCP
Mouse Sperm Proteomic Profiling - University of Newcastle - Dr. Matt Dun
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2018-06-24 | MSV000082497 | MassIVE
TranscriptomicsBiogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals (single embryo)
Parental dietary conditions can influence the metabolic traits of offspring. In mice, paternal consumption of low protein diet alters cholesterol and lipid metabolism of progeny. Here, we examine RNA species expressed in male reproductive tissues of mice. Protein restriction leads to altered levels ...
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-75765 | biostudies-arrayexpress
TranscriptomicsBiogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals
Parental dietary conditions can influence the metabolic traits of offspring. In mice, paternal consumption of low protein diet alters cholesterol and lipid metabolism of progeny. Here, we examine RNA species expressed in male reproductive tissues of mice. Protein restriction leads to altered levels ...
ORGANISM(S): Mus musculus 
2016-01-04 | E-GEOD-74537 | biostudies-arrayexpress
ProteomicsBovine sperm plasma membrane proteomics through biotinylation and subcellular enrichment
Mammalian fertilization requires a complex interplay between a sperm cell and an oocyte. A significant proportion of these functions are mediated through the proteomic composition of the sperm surface. These proteomic constituents can present as biomarkers to control and regulate breeding of agricul...
ORGANISM(S): Bos taurus (Bovine) 
2015-03-19 | PXD001096 | Pride
Plasma membrane proteome Reproductive biology Biotinylation Bos taurus Sperm cell 
TranscriptomicsPlastics Derived Endocrine Disruptors (BPA, DEHP and DBP) Induce Epigenetic Transgenerational Inheritance of Obesity, Reproductive Disease and Sperm Epimutations
Environmental compounds are known to promote epigenetic transgenerational inheritance of adult onset disease in subsequent generations (F1M-bM-^@M-^SF3) following ancestral exposure during fetal gonadal sex determination. The current study was designed to determine if a mixture of plastic derived en...
ORGANISM(S): Rattus norvegicus 
2014-07-22 | E-GEOD-59555 | biostudies-arrayexpress
TranscriptomicsGenes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm
In mature human sperm, genes of importance for embryo development (i.e. transcription factors) lack DNA methylation and bear nucleosomes with distinctive histone modifications, suggesting the specialized packaging of these developmental genes in the germline. Here, we explored the tractable zebrafis...
ORGANISM(S): Danio rerio 
2011-01-13 | E-GEOD-26609 | biostudies-arrayexpress
ProteomicsProteomic analysis of dimorphic sperm in the Cabbage White Butterfly, Pieris rapae
Sperm dimorphism, the production of two distinct sperm morphs by a single male, is a widespread but poorly understood reproductive phenomenon. In Lepidoptera, fertilizing eupyrene sperm coexist with anucleate apyrene sperm, which cannot fertilize eggs but are nevertheless required for successful rep...
ORGANISM(S): Pieris rapae rapae 
2026-03-23 | PXD070767 | Pride
Lc-ms 
TranscriptomicsCharacterization of the small RNA population in Human spermatozoa
Small noncoding RNAs (sncRNA) are becoming recognized for their participation in a diverse range of cellular functions. In this study, their global characterization in human spermatozoa from donors with proven fertility was undertaken. Reads were analyzed in two classes, those mapping to unique loca...
ORGANISM(S): Homo sapiens 
2011-10-15 | E-GEOD-21191 | biostudies-arrayexpress
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