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ProteomicsEvaluation of burbot Lota lota spermatozoon motility, lipid composition, protein profile, and swelling rate following change of temperature and osmolality
Despite available information on the roles of osmotic pressure, potassium (K+), and calcium (Ca2+) in activation of Eurasian burbot spermatozoon motility, the changes in sperm biochemical composition and mechanisms underlying their activation at temperatures above optimal spawning temperature is sti...
ORGANISM(S): Lota lota 
2022-09-20 | PXD027402 | Pride
Biomolecule Protein Fish lipid Sperm activation Osmolality 
TranscriptomicsThe Partitioning of RNAs in sperm
A diverse pool of RNAs remain encapsulated within the transcriptionally and translationally silent spermatozoon. These transcripts persist within the male gamete despite the dramatic reduction in cellular volume achieved through expulsion of the cytoplasm and quite possibly the nucleoplasm. The prec...
ORGANISM(S): Mus musculus 
2015-07-08 | E-GEOD-62874 | biostudies-arrayexpress
ProteomicsEvaluation by re-derivation of a paternal line after 18th generations on seminal traits, proteome and fertility: spermatozoon membrane proteins Spectral Library
Breeding schemes for meat production in rabbits involved a three-way cross of specialized lines in which a paternal line inseminates maternal crossbred females. Paternal line or terminal sire are selected for growth traits, being the males used for the production of fertile dose at the insemination ...
ORGANISM(S): Oryctolagus cuniculus cuniculus 
2020-01-13 | PXD015510 | Pride
Dia-lc/msms Fertility Swath Spermatozoon membrane protein 
TranscriptomicsExpression data from yeast heterologously expressing alpha-ENaC, CFTR or Kir2.1 [CFTR]
Misfolded membrane proteins are retained in the endoplasmic reticulum (ER) and are subject to the ER associated degradation pathway, which clears the secretory pathway of potentially toxic species. While the transcriptional response to environmental stressors has been extensively studied, limited d...
ORGANISM(S): Saccharomyces cerevisiae 
2014-09-10 | E-GEOD-61244 | biostudies-arrayexpress
TranscriptomicsExpression data from yeast heterologously expressing alpha-ENaC, CFTR or Kir2.1 alpha-ENaC]
Misfolded membrane proteins are retained in the endoplasmic reticulum (ER) and are subject to the ER associated degradation pathway, which clears the secretory pathway of potentially toxic species. While the transcriptional response to environmental stressors has been extensively studied, limited d...
ORGANISM(S): Saccharomyces cerevisiae 
2014-09-10 | E-GEOD-61243 | biostudies-arrayexpress
TranscriptomicsExpression data from yeast heterologously expressing alpha-ENaC, CFTR or Kir2.1 [Kir2.1]
Misfolded membrane proteins are retained in the endoplasmic reticulum (ER) and are subject to the ER associated degradation pathway, which clears the secretory pathway of potentially toxic species. While the transcriptional response to environmental stressors has been extensively studied, limited d...
ORGANISM(S): Saccharomyces cerevisiae 
2014-09-10 | E-GEOD-61245 | biostudies-arrayexpress
ProteomicsQuantitative proteomic analysis of seminal plasma, sperm membrane proteins and seminal extracellular vesicles suggests vesicular mechanisms aid in the removal and addition of proteins to the ram sperm membrane.
Quantitative proteomic studies are contributing greatly to our understanding of the spermatozoon through the provision of detailed information on the proteins spermatozoa acquire and shed in the acquisition of fertility. Extracellular vesicles (EVs) are thought to aid in the delivery of proteins to ...
ORGANISM(S): Ovis aries 
2020-05-08 | PXD017537 | Pride
Prostasomes Microvesicles Edil3 Epididysomes Sperm surface 
TranscriptomicsIdentification of markers of responsiveness in rheumatoid arthritis patients
Despite the increasing of available drugs in RA, the overall rate of non response is 30 to 40% of treated patients. To optimize the drug prescription and better elaborate the therapeutic strategies, gene profiling in PBMCs was used to predict the responsiveness to anakinra. Thirty two patients treat...
ORGANISM(S): Homo sapiens 
2010-06-26 | E-GEOD-11827 | biostudies-arrayexpress
TranscriptomicsIsolation and next generation sequencing of epididymal extracellular vesicles reveals segmental patterns of miRNA expression and a potential mechanism for modification of the sperm epigenome.
Interest in the sperm epigenome continues to grow in view of the realization that it is vulnerable to dynamic modifications arising from a variety of paternal environment exposures and that this legacy can serve as an important determinant of intergenerational inheritance. It has been postulated tha...
ORGANISM(S): Mus musculus 
2016-08-25 | E-GEOD-79500 | biostudies-arrayexpress
UnknownThe vertebrate- and testis- specific transmembrane protein C11ORF94 plays a critical role in sperm-oocyte membrane binding.
Not available
S-EPMC9437168 | biostudies-literature
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