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TranscriptomicsRegulation of human endothelial gene expression by miR-126
Fish, JE, Santoro, MM, Morton, SU, Yu, S, Yeh, RF, Wythe, JD, Ivey, KI, Bruneau, BG, Stainier, DYR, and Srivastava, D. (2008). miR-126 Regulates Angiogenic Signaling and Vascular Integrity. Developmental Cell 15, 272-284. Precise regulation of the formation, maintenance, and remodeling of the vascu...
ORGANISM(S): Homo sapiens 
2008-08-12 | E-GEOD-12011 | biostudies-arrayexpress
TranscriptomicsA Regulatory Pathway Involving Notch1/β-Catenin/Isl1 Determines Cardiac Progenitor Cell Fate
The regulation of multipotent cardiac progenitor cell (CPC) expansion and subsequent differentiation into cardiomyocytes, smooth muscle, or endothelial cells is a fundamental aspect of basic cardiovascular biology and cardiac regenerative medicine. However, the mechanisms governing these decisions r...
ORGANISM(S): Mus musculus 
2009-05-13 | E-GEOD-15232 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of uterine stromal cells isolated from Hand2 floxed and Hand2 ablated mice on day 4 of pregnancy
Our previous study revealed that the basic helix-loop-helix transcription factor Hand2 is a downstream target of progesterone signaling in mouse uterine stroma at the time of implantation. Further, conditional deletion of Hand2 in mouse uterus leads to implantation failure due to impaired uterine ep...
ORGANISM(S): Mus musculus 
2011-06-03 | E-GEOD-25881 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in mouse skNAC knockout heart at E11.5
Targeted deletion of skNAC in mice resulted in early embryonic lethality with cardiac defects. In order to investigate the molecular mechanism of the cardiac defect, we designed the microarray comparing gene expression of the mutant E11.5 heart to wild type E11.5 heart. Keywords: genetic modificat...
ORGANISM(S): Mus musculus 
2010-11-19 | E-GEOD-5841 | biostudies-arrayexpress
TranscriptomicsGene expression in mouse embyonic cardiomyocytes, fibroblasts and adult cardiac fibroblasts
Growth and expansion of ventricular chambers is essential during cardiogenesis and is achieved by proliferation of cardiac progenitors that are not fully differentiated. Disruption of this process can lead to prenatal lethality. In contrast, adult cardiomyocytes achieve growth through hypertrophy ra...
ORGANISM(S): Mus musculus 
2009-01-14 | E-GEOD-14412 | biostudies-arrayexpress
TranscriptomicsGene expression in b1-integrin wild-type and knockout mouse heart
Growth and expansion of ventricular chambers is essential during cardiogenesis and is achieved by proliferation of cardiac progenitors that are not fully differentiated. Disruption of this process can lead to prenatal lethality. In contrast, adult cardiomyocytes achieve growth through hypertrophy ra...
ORGANISM(S): Mus musculus 
2009-01-14 | E-GEOD-14411 | biostudies-arrayexpress
ProteomicsProteomic analysis links truncated tau to lysosome motility, autophagy and endo-lysosomal dysfunction
Tauopathies are characterized by the progressive accumulation of abnormal tau species, which disrupt the autophagy-lysosomal pathway (ALP), a critical system for degrading intracellular macromolecules and aggregated proteins, causing toxicity and cell death. This study investigates the impact of the...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-22 | PXD062128 | Pride
Tauopathies Toxicity Proteomics Mass spectrometry Autosomal 
TranscriptomicsShear Stress and NOTCH1 Regulate Calcification Related Genes in Human Aortic Valve Endothelium
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-05-16 | E-GEOD-47160 | biostudies-arrayexpress
GenomicsHomo sapiens
Regulation of human endothelial gene expression by miR-126
PRJNA114301 | ENA
GenomicsDanio rerio
Regulation of zebrafish endothelial gene expression by miR-126
PRJNA114303 | ENA
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