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ProteomicsPlasma proteomics in Stabilin-1 and Stabilin-2 knock-out mice
Scavenger receptors Stabilin-1 (Stab1) and Stabilin-2 (Stab2) are preferentially expressed by liver sinusoidal endothelial cells. They mediate the clearance of circulating plasma molecules controlling distant organ homeostasis. Studies suggest that Stab1 and Stab2 may impact atherosclerosis. Althoug...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-21 | PXD029342 | Pride
Apoe Plasma Stabilin Lc-ms/ms 
ProteomicsStabilin-2 is a clearance receptor for multiple procoagulant plasma ligands Short title: Stabilin-2 plasma ligands
Damaging STAB2 gene variants are associated with increased venous thromboembolic risk. STAB2 encodes stabilin-2, a clearance receptor, expressed by the liver and spleen. Given its function, it is likely that the prothrombotic state associated with stabilin-2 deficiency is due to reduced procoagulant...
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD055782 | Pride
Stabilin-2 Thrombosis Turboid 
TranscriptomicsTranscriptome of Stabilin-1 siRNA transfected human monocytes
Stabilin-1/CLEVER-1 is a multidomain protein present in lymphatic and vascular endothelial cells and in M2 immunosuppressive macrophages. Stabilin-1 functions in scavenging, endocytosis and leukocyte adhesion to and transmigration through the endothelial cells. We have analyzed the putative function...
ORGANISM(S): Homo sapiens 
2015-11-30 | GSE63807 | GEO
TranscriptomicsGene expression analysis of Stabilin-1 positive human monocytes
Stabilin-1/CLEVER-1 is a multidomain protein present in lymphatic and vascular endothelial cells and in M2 immunosuppressive macrophages. Stabilin-1 functions in scavenging, endocytosis and leukocyte adhesion to and transmigration through the endothelial cells. We analyzed the putative functions of ...
ORGANISM(S): Homo sapiens 
2015-11-30 | GSE63519 | GEO
TranscriptomicsEndocytic and signalling function of stabilin-1 in tumor associated macrophages
Stabilin-1 is a scavenger/sorting receptor expressed by sinusoidal endothelial cells, alternatively-activated and tumor-associated macrophages (TAM) in several types of human cancer and mouse tumor models. We have found abundant expression of stabilin-1 on TAM in mouse model of mammary adenocarcinom...
ORGANISM(S): Mus musculus 
2014-10-30 | E-GEOD-55595 | biostudies-arrayexpress
TranscriptomicsEndocytic and signalling function of stabilin-1 in tumor associated macrophages
Stabilin-1 is a scavenger/sorting receptor expressed by sinusoidal endothelial cells, alternatively-activated and tumor-associated macrophages (TAM) in several types of human cancer and mouse tumor models. We have found abundant expression of stabilin-1 on TAM in mouse model of mammary adenocarcinom...
ORGANISM(S): Mus musculus 
2014-10-30 | GSE55595 | GEO
GenomicsTranscriptome of liver tissue in 2 week old and E17.5 Stabilin-1 knock-out mice
Transcriptome of liver tissue in 2 week old and E17.5 Stabilin-1 knock-out mice
PRJNA473361 | ENA
TranscriptomicsTranscriptome of liver tissue in 5 week old Stabilin-1 knock-out mice
Stabilin-1/CLEVER-1 is a multidomain protein present in lymphatic and vascular endothelial cells and in M2 immunosuppressive macrophages. Stabilin-1 functions in scavenging, endocytosis and leukocyte adhesion to and transmigration through the endothelial cells.
ORGANISM(S): Mus musculus 
2016-07-15 | GSE78752 | GEO
UnknownStabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver.
Not available
S-EPMC4824115 | biostudies-literature
UnknownDeficiency for scavenger receptors Stabilin-1 and Stabilin-2 leads to age-dependent renal and hepatic depositions of fasciclin domain proteins TGFBI and Periostin in mice.
Not available
S-EPMC10497815 | biostudies-literature
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