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MetabolomicsMetabolomics reveals stage-specific internal quality deterioration and distinct metabolic changes in egg albumen and yolk during storage

Internal quality of chicken eggs deteriorates during storage, but the biochemical changes occurring in albumen and yolk over storage time remain insufficiently characterized. This study investigated changes in internal quality traits and specific metabolite profiles in albumen and yolk of chicken...

2026-07-17 | MTBLS15068 | MetaboLights
ProteomicsDifferential protein phosphorylation during stage conversion in Toxoplasma gondii
The intracellular parasite Toxoplasma gondii resides within a membrane bound parasitophorous vacuole and secretes an array of proteins to establish this replicative niche during acute stage of infection. When rapidly dividing tachyzoites convert to chronic stage bradyzoites, many secreted proteins a...
ORGANISM(S): Homo sapiens (Human) Toxoplasma gondii ME49 
2020-06-12 | PXD019729 | Pride
Stage conversion Bradyzoites Phosphorylation Tachyzoites Toxoplasma 
ProteomicsAP2-HS and a GDV1 regulatory feedback loop mediate environmental induction of sexual conversion in Plasmodium falciparum
Transmission of Plasmodium spp. from a human host to a mosquito vector requires that some parasites abandon the asexual replicative cycle in the blood, associated with all clinical symptoms of malaria, and convert into non-replicative sexual precursors called gametocytes. The sexual conversion rate ...
ORGANISM(S): Plasmodium falciparum 
2026-07-28 | PXD064373 | Pride
Plasmodium falciparum Dha Sexual conversion Choline-depletion 
TranscriptomicsDissecting engineered cell types and enhancing cell fate conversion via CellNet
Engineering clinically relevant cells in vitro holds promise for regenerative medicine, but most protocols fail to faithfully recapitulate target cell properties. To address this, we developed CellNet, a network biology platform that determines whether engineered cells are equivalent to their target...
ORGANISM(S): Mus musculus 
2014-08-14 | E-GEOD-59037 | biostudies-arrayexpress
TranscriptomicsRNA-seq timeline of fibroblast to neuron conversion using traditional NC media and NC+ZPAK media
Bulk RNA was extracted via trizol at Fibroblasts stage, 5 days, 10 days, 15 days, and 20 days of fibroblast to neuron conversion using traditional NC media, or NC media supplemented with ZM336372, pyrintegrin, AZ960, and KC7F2
ORGANISM(S): Homo sapiens 
2019-05-23 | E-MTAB-7250 | biostudies-arrayexpress
TranscriptomicsSerotonergic regulation of melanocyte conversion: a bioelectric network explains stochastic all-or-none hyperpigmentation
Depolarization of resting membrane potential in select cells in Xenopus larvae induces striking hyperpigmentation due to dysregulation of melanocytes. Here, we show that this non-cell-autonomous process is mediated by cAMP, CREB, and the transcription factors Sox10 and Slug. Our microarray analysis ...
ORGANISM(S): Xenopus laevis 
2015-11-03 | E-GEOD-70834 | biostudies-arrayexpress
TranscriptomicsGene expression in Entamoeba histolytica cysts and trophozoites
We compared multiple strains of lab trophozoites to recent clinical isolates. Clinical isolates were grown in xenic media, and maintained many characteristics of the cyst stage of devlopment Keywords: Stage conversion E. histolytica trophozoites of three different strains (HM1:IMSS, Rahman, and 200:...
ORGANISM(S): Entamoeba histolytica 
2007-03-01 | E-GEOD-6648 | biostudies-arrayexpress
GenomicsPfAP2-G ChIP-seq in stage I gametocytes derived via next cycle conversion (NCC) and same cycle conversion (SCC)
PfAP2-G ChIP-seq in stage I gametocytes derived via next cycle conversion (NCC) and same cycle conversion (SCC)
PRJNA554600 | ENA
GenomicsA unique regulatory phase of DNA methylation in the early mammalian embryo
DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly accepted that the paternal genome is actively depleted of global cytosine methylation at fertilization, followed by passive depletion that reaches a minimum at the blastocyst stage. However, this model is based on limit...
ORGANISM(S): Mus musculus 
2012-03-28 | E-GEOD-34864 | biostudies-arrayexpress
TranscriptomicsThe Central Role of c-Myc during Malignant Conversion in Human Hepatocarcinogenesis
Hepatocarcinogenesis is a multi-stage process in which precursor lesions progress into early hepatocellular carcinomas (eHCC) by sequential accumulation of multiple genetic and epigenetic alterations. To decode the molecular events during early stages of liver carcinogenesis, we performed gene expre...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-12443 | biostudies-arrayexpress
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