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ProteomicsPattern Analysis of Organellar Maps for Interpretation of Pro-teomic Data
The human proton-coupled folate transporter (PCFT) was stably expressed as a fu-sion protein with a BioID2-HA in the C-terminal position (PCFT-BioID2). The uncom-plxed biotin transferase was used as a control to identify proteins that are biotinylated randomly due to sheer abundance and/or an unnatu...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD032297 | Pride
Proteomics  pattern analysis  bioinformatics  proximity labeling 
ProteomicsComparative secretome analysis after particulate exposure in human lung cell culture models
2D (A549) and 3D (AIR-606) human lung epithelial cell cultures were mock treated or exposed to 100 ug/ml petroleum coke or urban air particulates (both in the PM10 range) for 16 h. Secretomes were compared for triplicate treatments for each group by isobaric tags and LC/MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2018-03-26 | PXD005194 | Pride
Lung Human Particulate matter Secretome Petroleum coke 
ProteomicsImmunological Sexual Dimorphism in Placenta and Its Response to Benzene Exposure
There is increasing concern regarding the adverse effects of air pollution on human health, and benzene is a major toxic compound in air pollution. Maternal benzene exposure has been associated with reproductive complications, such as preterm birth, low birth weight, and immunological and neurologic...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD035085 | Pride
Placenta Sexual dimorphism Pregnancy Maternal immune activation Benzene exposure 
ProteomicsThe anti-MRSA compound KCR inhibits protein synthesis in Staphylococcus aureus
S aureus was treated in triplicate with 3-O-alpha-L-(2",3"-di-p-coumaroyl)rhamnoside (KCR), oxacillin or vehicle and quantitative proteomic analysis was carried out using isobaric tags and mass spectrometry. 1190 proteins were identified and 552 were affected by KCR (q<0.01). Ontology analysis ide...
ORGANISM(S): Staphylococcus Aureus (ncbitaxon:1280) 
MSV000084282 | MassIVE
GenomicsGenomic Characterization of Meningiomas

Meningiomas are the most common primary brain tumor in the US. Although the tumor suppressor gene NF2 is disrupted in approximately half of meningiomas, the complete spectrum of genetic changes in meningiomas remains poorly understood, particularly in the large subset of tumors without NF2 altera...

phs000552.v1.p1 | EGA
ProteomicsThe human diabetes-specific visceral adipose tissue proteome: insights into mechanisms of adipose tissue dysfunction in metabolic disease
Introduction: The human adipose tissue proteome associated with type 2 diabetes (DM) is not well described. An understanding of the DM-specific adipose tissue proteome would provide insight into mechanisms underlying the pathogenesis of DM. Methods: We used label-free proteomics analysis to quanti...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-03-27 | MSV000085169 | MassIVE
ProteomicsSirtuin 5 Reduces Malonylation in Non-mitochondrial Metabolic Pathways in Diabetic Kidney Disease
Early diabetic kidney disease (DKD) is marked by dramatic metabolic reprogramming due to nutrient excess, mitochondrial dysfunction, and increased renal energy requirements from hyperfiltration. We hypothesized that changes in metabolism in DKD may be regulated by Sirtuin 5 (SIRT5), a deacylase that...
ORGANISM(S): Mus Musculus 
PXD037819 | panorama
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