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While growing in the human intestine, C. jejuni grows within the mucus layer. The largest constituents of this layer are the large mucin glycoproteins. A transcriptomic profile of C. jejuni NCTC11168 growing in a mucin-containing minimal medium seeks to describe the effect of the presence of mucin...
ORGANISM(S): Campylobacter jejuni 
Transcriptional profile of C. jejuni NCTC11168 while growing in MEM medium containing L-fucose. We hypothesize that certain C. jejuni strains, containing A certain genomic island, have acquired the ability to metabolize fucose. This study demonstrates the transcriptional profile C. jejuni growth w...
ORGANISM(S): Campylobacter jejuni 
Campylobacter jejuni is a widespread pathogen responsible for most of the food-borne gastrointestinal diseases in Europe. For pathogen control in the food industry, the use of natural antimicrobial molecules is a promising strategy to avoid antibiotic treatments. Isothiocyanates are natural antimicr...
ORGANISM(S): Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 
Transcriptional regulation mediates adaptation of pathogens to environmental stimuli and is important for host colonisation. The Campylobacter jejuni genome sequence reveals a surprisingly small set of regulators, mostly of unknown function, suggesting an intricate regulatory network. Interestingly,...
ORGANISM(S): Campylobacter jejuni 
Intestinal microbial dysbiosis is associated with Crohn’s disease (CD). However, the mechanisms leading to the chronic mucosal inflammation that characterizes this disease remain unclear. To evaluate causality and mechanisms of disease, we conducted a systems level study of the interactions between ...
ORGANISM(S): Homo sapiens (Human) 
2016-09-29 | PXD002882 | Pride
4 pan-Neisseria arrays examining the gonococcal response to iron availability. Dual channel (Cy3/Cy5) arrays, using random nonamers for cDNA generation. Arrays scanned with ScanArray ExpressHT microarray scanner. Data analyzed using ArrayVision 7.0 and compiled in GeneSpring.
ORGANISM(S): Neisseria gonorrhoeae 
The ferric uptake regulator Fur is a potential regulator of Campylobacter jejuni acid survival and cross-protection against other stresses
Exposure of Campylobacter jejuni to acid stress enhances its pathogenesis and cross-protects the bacterium against other stresses
Background: During gut colonization, the enteric pathogen C. jejuni has to surmount the toxic effects of reactive oxygen species produced by its own metabolism, by the host immune system and by the intestinal microflora. Elucidation of C. jejuni oxidative stress defense mechanisms is critical for u...
ORGANISM(S): Campylobacter jejuni subsp. jejuni NCTC 11168 
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