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TranscriptomicsVitamin A nutritional status and retinoic acid as regulators of gene expression in rat liver
Vitamin A (retinol) is an essential precursor for the production of retinoic acid (RA), which in turn is a major regulator of gene expression, affecting cell differentiation throughout the body. Understanding how vitamin A nutritional status, as well as therapeutic retinoid treatment, regulates the ...
ORGANISM(S): Rattus norvegicus 
2011-08-31 | E-GEOD-24104 | biostudies-arrayexpress
TranscriptomicsMapping the cellular and molecular landscape of cardiac non-myocytes in murine type-2 diabetes
Here we define key single-cell transcriptional alterations within cardiac non-myocytes, from ventricles of spontaneously type-2 diabetic (db/db) and control (db/h) mouse hearts ([B6.BKS(D)-Lepr/J], stock #000697). The cell preparation sequenced consisted of metabolically active, live and nucleat...
ORGANISM(S): Mus musculus 
2022-11-29 | E-MTAB-11940 | biostudies-arrayexpress
MetabolomicsExploring the Glucose Fluxotype of the E. coli y-ome Using High-Resolution Fluxomics
We have developed a robust workflow to measure high-resolution fluxotypes (metabolic flux phenotypes) for large strain libraries under fully controlled growth conditions. This was achieved by optimizing and automating the whole high-throughput fluxomics process and integrating all relevant software ...
2021-05-13 | MTBLS2188 | MetaboLights
UnknownPM2.5 of ambient origin: estimates and exposure errors relevant to PM epidemiology.
Not available
S-EPMC2553354 | biostudies-literature
ProteomicsThe proteomic landscape of parkin-deficient and parkin-overexpressing rat nucleus accumbens: an insight into the role of parkin in methamphetamine use disorder
In recent years, methamphetamine (METH) misuse in the US has been rapidly increasing, and there is no FDA-approved pharmacotherapy for METH use disorder (MUD). We previously determined that ubiquitin-protein ligase parkin is involved in the regulation of METH addictive behaviors in rat models of MUD...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-08-04 | PXD065059 | Pride
Parkin  proteome  nucleus accumbens  mitochondria  methamphetamine 
TranscriptomicsTranscription profiling of rat primary hepatocytes after acetaminophen-induced gene expression in sandwich-culture
Gene expression profiles of sandwich-cutlured primary rat hepatocytes exposed to 5 mM and 10 mM acetaminophen were used in a parallelogram approach in order to compare gene expression responses between rat and human using in vitro cellular models, heaptocytes, and between rat in vitro and in vivo Ex...
ORGANISM(S): Rattus norvegicus 
2009-01-14 | E-GEOD-13465 | biostudies-arrayexpress
ProteomicsComparison of SPEED, S-Trap, and In-Solution based sample preparation methods for tandem mass spectrometry
Bottom-up proteomic analyses rely on efficient protein extraction from tissue and proteolysis into peptides for mass spectrometry. Commonly used detergent-based strategies aid cell lysis and protein solubilization but are poorly compatible with downstream protein digestion and liquid chromatography-...
ORGANISM(S): Ovis aries 
2023-03-30 | PXD030797 | Pride
Speed Plasma Kidney Sheep Tripletof S-trap Dda 
UnknownStructural genomic variation and behavioral interactions underpin a balanced sexual mimicry polymorphism.
Not available
S-EPMC12129486 | biostudies-literature
GenomicsPopulation Architecture using Genomics and Epidemiology (PAGE): Causal Variants Across the Life Course (CALiCo): Coronary Artery Risk Development in Young Adults (CARDIA)

CALiCo CARDIA
The Coronary Artery Risk Development in Young Adults (CARDIA) Study is a study examining how heart disease develops in adults. It began in 1986 with a group of 5115 black and white men and women aged 18-30 years. The participants were selected so that there would be appr...

phs000236.v1.p1 | EGA
TranscriptomicsTelomeric DNA damage response activation mediates idiopathic pulmonary fibrosis caused by telomere dysfunction
Lungs from wild type and Terc KO mice, treated with DDR inhibitors
ORGANISM(S): Mus musculus 
2026-07-10 | E-MTAB-14908 | biostudies-arrayexpress
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