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ProteomicsThe Parkinson's disease protein alpha-synuclein is a direct modulator of Processing-bodies and mRNA stability
Hallacli E, Kayatekin C, Nazeen S, Wang XH, Sheinkopf Z, Sathyakumar S, Sarkar S, Jiang X, Dong X, Di Maio R, Wang W, Keeney MT, Felsky D, Sandoe J, Vahdatshoar A, Udeshi ND, Mani DR,Carr SA, de Jager P, Myers CL, Lindquist S, Greenmyre TJ, Bartel DP, Feany MB, Sunyaev S, Chung CY and Khurana V. Alp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-03-09 | MSV000089026 | MassIVE
ProteomicsComparative proteomic study on liver lipid droplets and mitochondria from mouse housed in different temperatures
Laboratory mice are standardly housed around 23ºC, setting them under chronic cold stress. Metabolic changes of liver in mice housed under thermoneutral, standard and cold temperatures remain unknown. Here we isolated lipid droplets and mitochondria from their livers for comparative proteomic study ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-07-17 | MSV000084105 | MassIVE
Genomics
Quantitative transcriptomic of Tricholoma matsutake fruiting bodies during cold storage
PRJNA718772 | ENA
UnknownProtein mobilities and P-selectin storage in Weibel-Palade bodies.
Not available
S-EPMC2923571 | biostudies-literature
TranscriptomicsTranscription profiling of livers from SCD1 knockout and wild type mice to elucidate the molecular basis of protection against adiposity in mice lacking of stearoyl-CoA desaturase-1 function
Stearoyl-CoA desaturase (SCD) is a central lipogenic enzyme catalyzing the synthesis of monounsaturated fatty acids, mainly oleate (C18:1) and palmitoleate (C16:1), which are components of membrane phospholipids, triglycerides, wax esters, and cholesterol esters. Several SCD isoforms (SCD1-3) exist ...
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2926 | biostudies-arrayexpress
UnknownStorage globulins pass through the Golgi apparatus and multivesicular bodies in the absence of dense vesicle formation during early stages of cotyledon development in mung bean.
Not available
S-EPMC3276096 | biostudies-literature
TranscriptomicsIntegrated omics studies delineate the formation and dynamics of lipid droplets in Rhodococcus opacus PD630 for biofuel feedstock
Purpose: To delineate mechanisms underlying lipid storage in LDs, we compared the transcriptomes of cells cultivated under three lipid-accumulating conditions. Methods: PD630 mRNA profiles of 3 different conditions (normal condition and LDs acculation conditions) were generated by deep sequencing, u...
ORGANISM(S): Rhodococcus opacus 
2013-11-04 | E-GEOD-42381 | biostudies-arrayexpress
ProteomicsAutofluorescence positive and negative microglia constitute novel subsets found in healthy brain.
Utilizing autofluorescence (AF) as a discriminating parameter, we identified two novel microglia subsets in both mice, termed autofluorescence-positive (AF+) and negative (AF-), and characterized them by label-free proteomics.
ORGANISM(S): Mus musculus (Mouse) 
2020-06-26 | PXD017505 | Pride
Autophagy Microglia Autofluorescence Aging Lipofuscin Storage-bodies 
ProteomicsA549 cells glucocorticoid treatment
This project aims to study the molecular signature of glucocorticoid treatment on A549 human lung adenocarcinoma cells on transcriptome and proteome levels. Glucocorticoid treatment was previously identified to induce formation of cytoplasmic Processing-bodies (P-bodies) in epithelial cell lines, wh...
ORGANISM(S): Homo sapiens (Human) 
2026-03-02 | PXD063431 | Pride
Glucocorticoid Epithelial a549 Dexamethasone Human Cell line 
TranscriptomicsVariants in PATL1 can cause intellectual disability in humans revealed by modeling in Drosophila and C. Elegans
P-bodies are dynamic, membrane-less organelles that function in mRNA metabolism that are involved in mRNA decay, storage, and translational repression. Here we introduce a new variant of the P-body protein encoding gene; PATL1, identified in an ID patient.
ORGANISM(S): Homo sapiens 
2026-04-10 | GSE326402 | GEO
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