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TranscriptomicsA novel extracytoplasmic function (ECF) sigma factor regulates virulence in Pseudomonas aeruginosa
Next to the two-component and quorum sensing systems, cell-surface signaling (CSS) has been recently identified as an important regulatory system in Pseudomonas aeruginosa. CSS senses signals from outside the cell and transmits them into the cytoplasm. It consists of a TonB-dependent outer membrane ...
ORGANISM(S): Pseudomonas aeruginosa 
2009-04-21 | E-GEOD-15697 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human oocytes from patients with polycystic ovary syndrome
Polycystic ovary syndrome (PCOS), the most common cause of anovulatory infertility, is characterized by increased ovarian androgen production, arrested follicle development, and is frequently associated with insulin resistance. These PCOS phenotypes are associated with exaggerated ovarian responsiv...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5850 | biostudies-arrayexpress
UnknownAlphaPept: a modern and open framework for MS-based proteomics.
Not available
S-EPMC10924963 | biostudies-literature
UnknownA novel mutation of LAMB2 in a multigenerational mennonite family reveals a new phenotypic variant of Pierson syndrome.
Not available
S-EPMC3223484 | biostudies-literature
UnknownRisk of Emergency Surgery or Death After Initial Nonoperative Management of Complicated Diverticulitis in Scotland and Switzerland.
Not available
S-EPMC7221865 | biostudies-literature
TranscriptomicsEffective Targeting of Quiescent Chronic Myelogenous Leukemia Stem Cells by Histone Deacetylase Inhibitors in Combination with Imatinib Mesylate
We investigated the ability of HDAC inhibitors (HDACi) to target CML stem cells. Treatment with HDACi combined with IM effectively induced apoptosis in quiescent CML progenitors resistant to elimination by IM alone, and eliminated CML stem cells capable of engrafting immunodeficient mice. In vivo ad...
ORGANISM(S): Homo sapiens 
2010-06-08 | E-GEOD-20876 | biostudies-arrayexpress
TranscriptomicsMechanisms of adaptation to stress and control of virulence in Pseudomonas aeruginosa: the OxyR regulons
Oxidative stress caused by exposure to reactive oxygen species (ROS), is a major challenge for aerobic and especially anaerobic organisms. Bacteria coordinate the response to oxidative stress through the LysR-type transcriptional regulator (LTTR) OxyR. Extensive studies have focused on the classical...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2013-12-13 | E-GEOD-33871 | biostudies-arrayexpress
UnknownAdenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis.
Not available
S-EPMC7977451 | biostudies-literature
UnknownNemvaleukin alfa, a modified interleukin-2 cytokine, as monotherapy and with pembrolizumab in patients with advanced solid tumors (ARTISTRY-1).
Not available
S-EPMC11580269 | biostudies-literature
ProteomicsMatrisome of neonatal mouse dermal fibroblasts
The goal of this project is to compare the protein composition of the extracellular matrices (ECMs) deposited in vitro by wild type, heterozygous, or SPAG17 KO neonatal mouse dermal fibroblasts.
ORGANISM(S): Mus musculus (Mouse) 
2022-09-22 | PXD019869 | Pride
Matrisome Fibrosis Spag17 Skin Fibroblast Ecm 
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