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TranscriptomicsPhysiological and molecular characterization of genetic competence in Streptococcus sanguinis
Streptococcus sanguinis is a major component of the oral flora and an important cause of infective endocarditis. The genome sequence of S. sanguinis strain SK36 was recently determined. A number of foreign genes acquired by natural transformation were detected, as well as orthologs of competence gen...
ORGANISM(S): Streptococcus sanguinis 
2011-01-21 | E-GEOD-21619 | biostudies-arrayexpress
ProteomicsProteomic characterization of extracellular membrane vesicles from Streptococcus sanguinis
Streptococcus sanguinis, a Gram-positive oral commensal, is highly prevalent in the oral cavity and well-characterized for its ability to antagonize oral pathobionts. We have found that production and dissemination of membrane vesicles by S. sanguinis is dependent on environmental and community fac...
ORGANISM(S): Streptococcus sanguinis SK36 
2024-10-17 | PXD041791 | Pride
Streptococcus sanguinis Membrane vesicles Commensalism Oral microbiome 
Transcriptomicsssa_1972-null mutant of Streptococcus sanguinis SK36
Transcriptional profiling of ssa_1972-null mutant of Streptococcus sanguinis compared with wild type. The ssa_1972 gene was inactivated in Streptococcus sanguinis SK36 and transcriptional profile was compared with wild type SK36. More information can be found at http://www.people.vcu.edu/~pingxu One...
ORGANISM(S): Streptococcus sanguinis SK36 
2013-07-17 | E-GEOD-48940 | biostudies-arrayexpress
ProteomicsEssential proteins' dynamics in Streptococcus sanguinis under antibiotic effect.
The current project investigates the proteomic profiles of essential genes, mass spectrometric analysis respectively, under impact of sub-inhibitory concentration of ampicillin (0.125 micro gm/ml), to elucidate the S. sanguinis stress response mechanisms on a temporal basis and define “pathogenesis ...
ORGANISM(S): Streptococcus sanguinis SK36 
2018-01-09 | PXD006479 | Pride
Streptococcus sanguinis Stress Antibiotic Oral Essential genes 
TranscriptomicsspxA1-null mutant of Streptococcus sanguinis SK36
Transcriptional profiling of the spxA1-null mutant of Streptococcus sanguinis SK36 compared with wild type. The spxA1 gene was inactivated in Streptococcus sanguinis SK36, and the mutant demonstrated opaque colony morphology, reduced hydrogen peroxide (H2O2) production, and reduced antagonistic acti...
ORGANISM(S): Streptococcus sanguinis 
2011-12-08 | E-GEOD-34203 | biostudies-arrayexpress
GenomicsStreptococcus sanguinis OH0843
Streptococcus sanguinis genome
PRJNA192961 | ENA
TranscriptomicsDifferential expression of genes in Streptococcus sanguinis nox mutant and its complemented strain
Transcriptional profiling of Streptococcus sanguinis nox mutant and its complemented strain compared to the wild-type SK36. Two experiments:nox mutant vs. SK36, nox complemeted strain vs. SK36. Biological replicates: triplicates, independently grown and harvested. Four replicate per array.
ORGANISM(S): Streptococcus sanguinis 
2015-05-04 | E-GEOD-68492 | biostudies-arrayexpress
GenomicsStreptococcus sanguinis
Streptococcus sanguinis Transcriptome or Gene expression
PRJNA564466 | ENA
GenomicsStreptococcus sanguinis
Streptococcus sanguinis Transcriptome or Gene expression
PRJNA730875 | ENA
TranscriptomicsDissecting the individual contribution of LuxS and autoinducer-2 activity on Streptococcus sanguinis SK36 biofilm formation by chemical, luxS-, and sahH-complementation
In a transcriptome based trail, we figured out that the deletion of luxS has a massive influence to cell growth and metabolism of Streptococcus sanguinis SK36. The biofilm defective luxS deletion mutant was comlemented by transgenic sahH from Pseudomonas aeruginosa. Thus 209 of 216 influenced genes ...
ORGANISM(S): Streptococcus sanguinis SK36 
2012-04-03 | E-GEOD-37007 | biostudies-arrayexpress
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