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UnknownSingle molecule measurements of DNA helicase activity with magnetic tweezers and t-test based step-finding analysis.
Not available
S-EPMC4967025 | biostudies-literature
UnknownThe spliceosomal phosphopeptide P140 controls the lupus disease by interacting with the HSC70 protein and via a mechanism mediated by gammadelta T cells.
Not available
S-EPMC2669294 | biostudies-literature
UnknownTG1050, an immunotherapeutic to treat chronic hepatitis B, induces robust T cells and exerts an antiviral effect in HBV-persistent mice.
Not available
S-EPMC4680198 | biostudies-literature
GenomicsEssential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
Malignant melanoma is an aggressive cancer known for its notorious resistance to most current therapies. The basic helix-loop-helix microphthalmia transcription factor (MITF) is the master regulator determining the identity and properties of the melanocyte lineage, and is regarded as a lineage-speci...
ORGANISM(S): Homo sapiens 
2014-12-13 | E-GEOD-64137 | biostudies-arrayexpress
GenomicsBRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (ChIP-seq)
Microphthalmia-associated transcription factor (MITF) is the master regulator of the melanocyte lineage. By tandem affinity purification and mass spectrometry, we present a comprehensive characterisation of the MITF interactome comprising multiple novel cofactors involved in transcription, DNA repli...
ORGANISM(S): Homo sapiens 
2015-04-02 | E-GEOD-61965 | biostudies-arrayexpress
TranscriptomicsBRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-04-02 | E-GEOD-61967 | biostudies-arrayexpress
UnknownExtracranial arteriovenous malformations demonstrate dysregulated TGF-β/BMP signaling and increased circulating TGF-β1.
Not available
S-EPMC9534897 | biostudies-literature
ProteomicsA combined proteomic and targeted analysis unravels new toxic mechanisms for zinc oxide nanoparticles in macrophages
The cellular responses of the J774 macrophage cell line to zinc oxide and zirconium oxide nanoparticles have been studied by a comparative quantitative, protein level based proteomic approach. The most prominent results have been validated by targeted approaches. These approaches have been carried o...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD002764 | Pride
Nanoparticles  macrophages  zinc oxide  zirconium dioxide  proteomics  glutathione biosynthesis  phagocytosis  dna damage  heme oxygenase  methyglyoxal  mitochondria 
UnknownThe "ART" of Epigenetics in Melanoma: From histone "Alterations, to Resistance and Therapies".
Not available
S-EPMC6993228 | biostudies-literature
UnknownThe nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells.
Not available
S-EPMC8233335 | biostudies-literature
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