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ProteomicsMitotic chromosome scaffold
Quantitative proteomics analysis of mitotic chromosome scaffold based on SILAC
ORGANISM(S): Gallus Gallus 
2018-10-07 | PXD007269 | JPOST Repository
Proteomicsmitotic chromosome scaffold SMC2ON vs OFF
Quantitative proteomics analysis of mitotic chromosome scaffold based on SILAC
ORGANISM(S): Gallus Gallus 
2018-10-07 | PXD008429 | JPOST Repository
TranscriptomicsSMC5/6 facilitates joint molecule resolution and stepwise loss of cohesin to promote meiotic chromosome segregation
During meiosis, Structural Maintenance of Chromosome (SMC) complexes underpin two fundamental features of meiosis: homologous recombination and chromosome segregation. While meiotic functions of the cohesin and condensin complexes have been delineated, the role of the third SMC complex, Smc5/6, rema...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-27 | E-GEOD-44852 | biostudies-arrayexpress
TranscriptomicsSingle cell Hi-C reveals cell-to-cell variability in chromosome structure
Large-scale chromosome structure and spatial nuclear arrangement have been linked to control of gene expression and DNA replication and repair. Genomic techniques based on chromosome conformation capture assess contacts for millions of loci simultaneously, but do so by averaging chromosome conformat...
ORGANISM(S): Mus musculus 
2013-09-26 | E-GEOD-48262 | biostudies-arrayexpress
TranscriptomicsDistribution of segmental duplications in the context of higher order chromatin organisation of human chromosome 7
Background Segmental duplications (SDs) are not evenly distributed along chromosomes. The reasons for this biased susceptibility to SD insertion are poorly understood. Accumulation of SDs is associated with increased genomic instability, which can lead to structural variants and genomic disorders su...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-41356 | biostudies-arrayexpress
TranscriptomicsTranscription-dependent positioning of Structural Maintenance of Chromosome complexes across the genome: RNA-Seq
The Structural Maintenance of Chromosomes (SMC) complexes regulate the chromosome structures essential for proper genome regulation and cell viability. In mammals, the coordinated actions of the SMC complexes condensin I, condensin II and cohesin regulate dynamic chromosome structures throughout th...
ORGANISM(S): Mus musculus 
2013-10-28 | E-GEOD-46316 | biostudies-arrayexpress
ProteomicsBAZ1A/B proteomics
SILAC analysis to comparing mitotic chromosome between Wild type and BAZ1B KO (or BAZ1A/B double KO)
ORGANISM(S): Homo Sapiens (human) 
2018-10-07 | PXD008696 | JPOST Repository
ProteomicsStructural maintenance of chromosomes (SMCs) proteins are required for developmental DNA elimination in Paramecium tetraurelia
To study the role of structural maintenance of chromosome (SMC)4-1 and SMC4-2 during programmed genome rearrangement in Paramecium tetraurelia. Paramecium SMC4-1 and SMC4-2 was tagged with 3 FLAG and HA at its C-terminal separately. The recombinant plasmid was microinjected into macronuclear and use...
ORGANISM(S): Paramecium tetraurelia 
2023-12-05 | PXD041826 | Pride
Paramecium tetraurelia Dna elimination Mitosis Structural maintenance of chromosome (smc) Meiosis 
TranscriptomicsSpatial rearrangement of the Streptomyces venezuelae linear chromosome during sporogenic development
Hi-C analysis of the chromosome organization during sporulation in Streptomyces venezuelae. The experiment includes the effect of ParA, ParB, SMC, and HupS proteins on the chromosome structure.
ORGANISM(S): Streptomyces venezuelae 
2020-12-09 | E-MTAB-9810 | biostudies-arrayexpress
TranscriptomicsChromosome conformation capture (Hi-C) analysis on lsr2, lsrL, and lsr2,lsrL deletion strains of S. venezuelae
Hi-C analysis of the chromosome organization during sporulation in Streptomyces venezuelae. The experiment includes the effect of lsr2 and lsrL deletions on the local and global chromosome architecture.
ORGANISM(S): Streptomyces venezuelae 
2026-01-01 | E-MTAB-16021 | biostudies-arrayexpress
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