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In order to explore the functions of carbonic anhydrase VI (CAVI) more fully, we examined the transcriptomic responses to CAVI deficiency in the submandibular gland, stomach, and duodenum of Car6-/- mice by cDNA microarray. 94, 56, and 127 genes were up- or down-regulated in the above-mentioned tiss...
ORGANISM(S): Mus musculus 
Salivary gland hypofunction lacks effective regenerative treatment, and organ-specific decellularized extracellular matrix scaffolds represent a promising biomaterial platform for tissue engineering. In this study, rat submandibular glands were decellularized using a rapid S3T1 workflow consisting o...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-04-21 | PXD077315 | Pride
To compare the gene expression profile of submandibular gland stem cells to submandibular gland epithelia, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the differential expression in the stem cells and the non-stem cell epithelia. Murin...
ORGANISM(S): Mus musculus 
Prostatic acid phosphatase is the main acid phosphatase in mouse submandibular salivary gland
ORGANISM(S): Mus musculus 
Oral microbial homeostasis is a key factor affecting oral health, and saliva plays a significant role in maintaining oral microbial homeostasis. The submandibular gland (SMG) and sublingual gland (SLG) together produce the most saliva at rest. Organic ingredients, including antimicrobial proteins, a...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-03 | PXD038423 | Pride
The goal of this study was to generate a spatiotemporal atlas of gene expression in the developing salivary gland. This will allow us to identify changes in gene expression that may result in the formation of the different domains of the salivary gland. At least 4 microarrays per location per time ...
ORGANISM(S): Mus musculus 
In this study we have explored the effects of ERdj5 chaperone protein deletion in the proteome of 129SV mouse submandibular salivary glands. This knockout mouse model recapitulates many aspects of Sjögren’s Syndrome, including salivary gland inflammatory infiltrations, anti-nuclear autoantibodies an...
ORGANISM(S): Mus musculus (Mouse) 
2021-06-21 | PXD026424 | Pride
To reveal novel molecular factors behind the development of salivary gland cancer, we performed gene expression analyses from Smgb-Tag mouse salivary gland samples. The overall purpose was to apply these results for clinical use to find new approaches for both possible therapeutic targets and more a...
ORGANISM(S): Mus musculus 
Ionizing Radiation-induced Acute Damage in the Submandibular Gland
Rapamycin treatment of AKT induced salivary gland tumors Normal tissue (parotid and submandibular), untreated tumor tissue, and tumor tissue treated for 3/14 days
ORGANISM(S): Mus musculus 
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