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ProteomicsC-BERST: Defining subnuclear proteomic landscapes at genomic elements with dCas9-APEX2
Mapping proteomic composition at distinct genomic loci and subnuclear landmarks in living cells has been a long-standing challenge. Here we report that dCas9-APEX2 Biotinylation at genomic Elements by Restricted Spatial Tagging (C-BERST) allows the unbiased mapping of proteomes near defined genomic ...
ORGANISM(S): Homo sapiens (Human) 
2018-05-07 | PXD009216 | Pride
Apex2 Biotinylation Centromere Proteomes Cas9 Subnuclear Telomere 
GenomicsSubnuclear genome compartmentalization controls bivalent chromatin activity
Subnuclear genome compartmentalization controls bivalent chromatin activity
PRJNA1144500 | ENA
GenomicsSubnuclear genome compartmentalization controls bivalent chromatin activity [RNA-seq]
Subnuclear genome compartmentalization controls bivalent chromatin activity [RNA-seq]
PRJNA1144501 | ENA
GenomicsA phase separated active subnuclear compartment safeguards repressive chromatin domains [iCLIP]
A phase separated active subnuclear compartment safeguards repressive chromatin domains [iCLIP]
PRJNA937859 | ENA
GenomicsA phase separated active subnuclear compartment safeguards repressive chromatin domains [RNA-seq]
A phase separated active subnuclear compartment safeguards repressive chromatin domains [RNA-seq]
PRJNA937855 | ENA
GenomicsA phase separated active subnuclear compartment safeguards repressive chromatin domains [ChIP-seq]
A phase separated active subnuclear compartment safeguards repressive chromatin domains [ChIP-seq]
PRJNA937860 | ENA
GenomicsA phase separated active subnuclear compartment safeguards repressive chromatin domains [TSA-seq]
A phase separated active subnuclear compartment safeguards repressive chromatin domains [TSA-seq]
PRJNA937861 | ENA
UnknownIdentification of a common subnuclear localization signal.
Not available
S-EPMC1995723 | biostudies-literature
OtherSubnuclear genome compartmentalization controls bivalent chromatin activity
The nuclear genome is spatially organized into a three-dimensional architecture by physical association of large chromosomal domains with subnuclear compartments including the nuclear lamina at the radial periphery and nuclear speckles within the nucleoplasm1,2,3,4,5. However, how higher-order spati...
ORGANISM(S): Homo sapiens 
2025-08-06 | GSE274038 | GEO
UnknownAn SVM-based system for predicting protein subnuclear localizations.
Not available
S-EPMC1325059 | biostudies-literature
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