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ProteomicsIP of endogenous SUMO2/3 in HEK293 cells
Aim of the experiments was to identify endogenously SUMO2/3 modified proteins in HEK293 cells. Cells were treated with dexamethasone (dex) or vehicle (etoh) and with heatshock (+43C, HS) or normal growth temperature (+37C, non-HS). Cells were induced with tetracycline to express BirA*-GR (glucocorti...
ORGANISM(S): Homo sapiens (Human) 
2021-01-11 | PXD017714 | Pride
Sumo2/3 Heatshock Immunoprecipitation Hek293 
ProteomicsProteomic Discovery of 2-AAA–Binding SAE1 and SUMO2/3-Related POLR2A
This dataset contains two types of proteomics experiments. First, we performed affinity-based pulldown assays using biotin-conjugated 2-aminoadipic acid (2-AAA) to identify proteins that directly bind to this metabolite. Second, we conducted SUMO1 or SUMO2/3 immunoprecipitation followed by LC-MS/MS ...
ORGANISM(S): Homo sapiens (Human) 
2026-08-04 | PXD070076 | Pride
Sae1 2-aminoadipic acid (2-aaa) Polr2a Aass Lc-ms/ms 
ProteomicsProteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells
SUMOylation is a form of post-translational modification involving covalent attachment of SUMO (Small Ubiquitin-like Modifier) polypeptides to specific lysine residues in the target protein. In human cells, there are four SUMO proteins, SUMO1–4, with SUMO2 and SUMO3 forming a closely related subfami...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080699 | MassIVE
ProteomicsSUMO2/3 IP of chromatin samples from WT and RNF4 knockout B cells
SUMO2/3 IP of chromatin samples from WT and RNF4 knockout B cells
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-12-13 | MSV000093661 | MassIVE
UnknownSUMO2/3 conjugation of TDP-43 protects against aggregation.
Not available
S-EPMC11844728 | biostudies-literature
GenomicsHeat shock-induced changes in chromatin binding of SUMO2/3 modified proteins
Heat shock induces rapid modification of proteins with SUMO2/3. This study concentrated in charaterizing how these changes are reflected on SUMOylation of chromatin bound proteins, trancsription, and chromatin binding of SUMO ligase PIAS1. Comparison of chromatin SUMO2/3 modification pattern in non-...
ORGANISM(S): Homo sapiens 
2015-07-02 | E-GEOD-66448 | biostudies-arrayexpress
UnknownComprehensive identification of SUMO2/3 targets and their dynamics during mitosis.
Not available
S-EPMC4074068 | biostudies-literature
ProteomicsChromatome of AR and SUMO2/3 idenitified with RIME
We identifyied AR and SUMO2/3 chromatomes in castration-resistant prostate cancer cells (VCaP) and studied the impact on SUMOylation inhibition (SUMOi)on them utilizing small molecule inhibitor ML792. Chromatome members were identifyied with Rapid Immunoprecipitation Mass spectrometry of Endogenous ...
ORGANISM(S): Homo sapiens (Human) 
2024-08-08 | PXD039179 | Pride
Ar Sumoylation Rime Chromatome Bruker timstof pro 
ProteomicsChromatomes of GR and SUMO2/3 identified with RIME
We identified GR and SUMO2/3 chromatomes in B-cell acute leukemia cells (NALM6) and studied the impact of SUMOylation inhibition (SUMOi) on them utilizing small molecule inhibitor ML792. Chromatome members were identified with Rapid Immunoprecipitation Mass spectrometry of Endogenous proteins (RIME)...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051304 | Pride
Human Cancer Immunoprecipitation Mass spectrometry Chromatin 
ProteomicsSUMO2/3 conjuagted proteins in kidney of IRI-AKI mice
the result of SUMO2/3 conjuagted proteins in kidney of IRI-AKI miceof using IP and LC-MS
ORGANISM(S): Mus Musculus 
2025-10-10 | PXD069295 |
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