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UnknownExtensive sequence divergence between the reference genomes of two elite indica rice varieties Zhenshan 97 and Minghui 63.
Not available
S-EPMC5024649 | biostudies-literature
ProteomicsThe COMPASS subunit Bre2 targets CRF Arp9 to regulate the bio-synthesis of secondary metabolite AFB1 and virulence in Aspergillus flavus
Aspergillus flavus, along with its notorious secondary metabolite aflatoxin B1 (AFB1), serious endangers human health. We previous revealed that histone methyltransferase complex COMPASS plays a crucial role in regulating various biological processes of A. flavus, but underlying mechanism is unclear...
ORGANISM(S): Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167) 
2026-02-08 | PXD060646 | Pride
Aspergillus flavus Histone methyltransferase Arp9 Chromatin remolding factor Bre2 
ProteomicsIdentification of key factors in cartilage tissue during the progression of osteoarthritis using a non-targeted metabolomics strategy
This work used non-targeted metabolomics and screened out differential metabolites and metabolic pathways, providing a reliable theoretical basis for further study of specific markers and their specific pathways in the progression of OA.
ORGANISM(S): Homo Sapiens 
2023-04-02 | PXD041287 |
UnknownBuilding two indica rice reference genomes with PacBio long-read and Illumina paired-end sequencing data.
Not available
S-EPMC5020871 | biostudies-literature
GenomicsTranscriptional Pause Release Is a Rate-Limiting Step for Somatic Cell Reprogramming (ChIP-seq)
Reactivation of the pluripotency network during somatic cell reprogramming by exogenous transcription factors involves chromatin remodeling and the recruitment of RNA polymerase II (Pol II) to target loci. Here, we report that Pol II is engaged at pluripotency promoters in reprogramming but remains ...
ORGANISM(S): Mus musculus 
2014-10-07 | E-GEOD-59828 | biostudies-arrayexpress
TranscriptomicsTranscriptional Pause Release Is a Rate-Limiting Step for Somatic Cell Reprogramming (RNA-seq)
Reactivation of the pluripotency network during somatic cell reprogramming by exogenous transcription factors involves chromatin remodeling and the recruitment of RNA polymerase II (Pol II) to target loci. Here, we report that Pol II is engaged at pluripotency promoters in reprogramming but remains ...
ORGANISM(S): Mus musculus 
2014-10-07 | E-GEOD-59813 | biostudies-arrayexpress
ProteomicsSecretomics and proteomics analysis of the Primary turmor cell and PC cells
Secretomics and proteomics analysis of the Primary turmor cell and PC cells
ORGANISM(S): Homo Sapiens 
2024-09-09 | PXD055731 |
ProteomicsDeep Multilayer Tissue Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression, human data
The molecular networks underlying Alzheimer’s disease (AD) are not well-defined. We present temporal profiling of >14,000 proteins and >34,000 phosphosites at the asymptomatic and symptomatic stages of AD, deep proteomics analysis of transgenic mouse models.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-17 | MSV000096123 | MassIVE
ProteomicsSerum proteomics identify biomarkers associated with the pathogenesis of idiopathic pulmonary fibrosis
This serum proteomic profile provides rigorous evidence that enables understanding of the heterogeneity of IPF and protein alterations that could help in its diagnosis and treatment decisions.
ORGANISM(S): Homo Sapiens 
2024-05-16 | PXD052329 |
ProteomicsPBRM1-deficient PBAF complexes target de novo genomic loci to activate pro-survival genes in clear cell renal cell carcinoma (PBRM1 dataset)
PBRM1 is lost in 40% of clear cell renal cell carcinomas (ccRCC) and the combined loss of VHL and PBRM1 drives ccRCC tumorigenesis. PBRM1 is an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler and despite its well-established role as a tumor suppressor, we have limited under...
ORGANISM(S): Homo Sapiens (human) 
2021-07-24 | PXD020554 | JPOST Repository
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