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TranscriptomicsA dysregulated Acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity
Acetylation of transcriptional regulators is normally dynamically regulated by nutrient status but is often persistently elevated in nutrient-excessive obesity conditions. We investigated the functional consequences of such aberrantly elevated acetylation of the nuclear receptor FXR as a model. Prot...
ORGANISM(S): Mus musculus 
2014-10-17 | E-GEOD-62414 | biostudies-arrayexpress
ProteomicsProteomics Profile of right ventricular remodeling at compensatory stage
Proteomics Profile of right ventricular remodeling at compensatory stage (both PAB and MCT models)
ORGANISM(S): Rattus Norvegicus 
PXD057041 |
ProteomicsMetabolomics analysis of Rivaroxaban
In this study, plasma metabolomes before and 3 hours after rivaroxaban intake in nonvalvular atrial ûbrillation (NVAF) patients and age/gender-matched controls were analyzed by liquid chromatography coupled with mass spectrometry (LC3MS/MS).
ORGANISM(S): Homo Sapiens 
PXD032247 |
ProteomicsMass spectrometry identification results of host proteins interacting with the NS1 protein of influenza B virus BYam-2018
Mass spectrometry identification results of host proteins interacting with the NS1 protein of influenza B virus BYam-2018
ORGANISM(S): Homo Sapiens 
2026-02-09 | PXD074269 |
ProteomicsPhosphoproteomic analysis of lettuce (Lactuca sativa L.) reveals starch and sucrose metabolism functions during bolting induced by high temperature
Temperature plays an important role in the growth and development of lettuce (Lactuca sativa L.). A high temperature can induce bolting, which decreases both the quality and production of lettuce. However, knowledge of underlying lettuce bolting is still lacking, especially in the molecular basis th...
ORGANISM(S): Lactuca Sativa Var. Capitata 
2019-06-10 | PXD014208 |
UnknownUltrabright ratiometric Raman-guided epilepsy surgery by intraoperatively visualizing proinflammatory microglia.
Not available
S-EPMC12208331 | biostudies-literature
ProteomicsLysine methylome features in EZH2 wild-type and mutant lymphoma cell line
We used EZH2i-targeted hematological malignancies as an examples and focused on molecular characterization of EZH2 Y641 mutant hematological cell lines. We used the proteomic strategies and compared the protein expression level and lysine methylation level (including mono-, di-, and trimethylaiton) ...
ORGANISM(S): Homo Sapiens 
2019-12-17 | PXD016779 |
ProteomicsInvestigating the off-target effects of Pro-BA using label-free and TMTpro quantitative proteomics
Nevertheless, in-depth characterization of the proteome could reveal unknown off-targets of Pro-BA. To address this issue, we repeated the same experiment but extended MS analysis time to 2 hours in this revision, which will be elaborated in the next point. Nonetheless, the computed p-value of ALK p...
ORGANISM(S): Homo Sapiens 
2025-03-25 | PXD062245 |
ProteomicsGlobal Profiling of RNA-Binding Protein Target Sites by LACE-seq
Proteomic analysis of Ago2-/- oocytes revealed that Ago2 interacted with endogenous small interfering RNAs (endo-siRNAs) to repress mRNA translation globally.
ORGANISM(S): Mus Musculus 
PXD025846 |
ProteomicsSubcommissural organ (SCO) contributes to brain development via SCO-secreted peptides
To explore the role of SCO and its functional mechanism, we measure the SCO-derived peptide in CSF from C57B/6 mice and SCO-ablated mice.
ORGANISM(S): Mus Musculus 
2025-02-04 | PXD040641 |
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