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ProteomicsHuman LC-MS, TMEM216 inhibits breast cancer lung metastasis by modulating IGF1R-IRS4 signaling pathway
Immunopurification and mass spectrometry analysis of TMEM216-associated proteins. Cellular extracts from Flag-TMEM216-expressing 293FT cells were affinity-purified. The eluates were resolved by SDS-PAGE and stained with Coomassie Brilliant Blue. The protein bands were retrieved and analyzed by mass ...
ORGANISM(S): Homo sapiens (Human) 
2026-05-31 | PXD061739 | Pride
Human 293ft cells 
UnknownGSK3β-mediated tau hyperphosphorylation triggers diabetic retinal neurodegeneration by disrupting synaptic and mitochondrial functions.
Not available
S-EPMC6251088 | biostudies-literature
ProteomicsS-nitrosylated cysteine residues identification in Staphylococcus aureus XN108
Staphylococcus aureus is a major human pathogen that causes diverse severe infections. The emergence of multi-drug resistance has caused S. aureus infection a global concern, especially resistance to vancomycin, a drug of last resort. A growing body of research focuses on the resistance mechanisms a...
ORGANISM(S): Staphylococcus Aureus 
2023-03-27 | PXD041143 |
ProteomicsRheb and TRF1 PhastID mass spectrometric data
Rheb is a small G protein that functions as the direct activator of the mechanistic target of rapamycin complex 1 (mTORC1) to coordinate signaling cascades in response to nutrients and growth factors. Despite extensive studies, the guanine nucleotide exchange factor (GEF) that directly activates Rhe...
ORGANISM(S): Homo Sapiens 
2022-09-29 | PXD037078 |
Proteomics[HPP-2.0] Proteomics data of cancers
proteomics data of multiple types of cancer including gatric, prostate, liver, thyoid, leukemia, bone, ovarian, cervical and lung tumors
ORGANISM(S): Homo Sapiens 
2024-02-02 | PXD049145 |
Proteomics4D label-free quantitative proteomics analysis of collagen-induced arthritis rats
4D label-free quantitative proteomics was performed to analysis the changes of protein expression in synovial tissues between Normal control group, Model control group and JTQBG treated group.
ORGANISM(S): Rattus Norvegicus 
2024-02-23 | PXD050056 |
ProteomicsIdentification and sequencing of CD36 interacting proteins in cardiomyocytes
Identification and sequencing of CD36 interacting proteins in cardiomyocytes
ORGANISM(S): Mus Musculus 
2024-10-11 | PXD056711 |
ProteomicsQuantitative Proteome Profiling of Maize Root zones Provides Insight into the Proteins Associated with Enhance Water Uptake in Maize
In order to get a better understanding of protein functions related to water uptake in maize, we investigated the proteome dynamics of cv. Anyu308 root system at three key zones divided into Upper root (0cm-20cm), Middle root (20cm-40cm), and Lower root (40cm-60cm) by label-free quantitative shotgun...
ORGANISM(S): Zea Mays 
2021-05-26 | PXD026269 |
ProteomicsREGγ is essential to maintain bone homeostasis by degrading TRAF6, preventing osteoporosis
Primary osteoporosis, manifesting as decreased bone mass and increased bone fragility, is a “silent disease” that is often ignored until a bone breaks. Accordingly, it is urgent to develop reliable biomarkers and novel therapeutic strategies for osteoporosis treatment. Here, we identified REGγ as...
ORGANISM(S): Homo Sapiens 
2024-10-27 | PXD057237 |
ProteomicsHSGA glioma tissue and benign tissue in Huashan Hospital
HSGA glioma tissue and benign tissue in Huashan Hospital
ORGANISM(S): Homo Sapiens 
2024-09-27 | PXD056311 |
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