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Hypoxia represents a major physiological challenge for prawns and is a problem in aquaculture. Therefore, an understanding of the metabolic response mechanism of economically important prawn species to hypoxia and re-oxygenation is essential. However, little is known about the intrinsic mechanisms b...
2021-05-17 | MTBLS584 | MetaboLights
To screen age-related regulators of mitophagy, we examined LC3-interacting proteins by proximity-dependent biotin identification. LC3B was cloned into a mammalian expression vector tagged with a mitochondrial OMM-targeted APEX2 (mito-APEX) label for proximity-based identification of LC3-interacting ...
ORGANISM(S): Homo sapiens (Human) 
2025-09-29 | PXD057110 | Pride
A total of 6081 proteins were identified in this study, of which 5267 proteins contained quantitative information. If taking 1.2 times as the change threshold and t-test p-value < 0.05 as the standard, the expression of 335 proteins in 92.1-a / 92.1 comparison group was up-regulated and 302 proteins...
ORGANISM(S): Homo sapiens (Human) 
2022-03-21 | PXD032215 | Pride
We describe the epigenetic profiling of the H3K9me2 and HP1a in Drosophila third instar larvae before and after CDK12 depletion by RNA interference (RNAi). Here we show that CDK12 regulates heterochromatin dynamics in Drosophila chromosomes. Depletion of CDK12 induces the increased HP1a and H3K9me2 ...
ORGANISM(S): Drosophila melanogaster 
CH891(1C), CH891(2A),CH891(1C+2A) and CH891 were sampled in leaf tissue at heading stage. The differentially expressed proteins in the proteome between transgenic restorer lines and recurrent parents were compared, and their functional annotation and enrichment analysis were performed
ORGANISM(S): Oryza sativa (Rice) 
2023-03-11 | PXD033443 | Pride
The anti-bacterial mechanism of the leaves of Strobilanthes cusia Kuntze against the Penicillin-resistant Streptococcus pneumoniae were analyzed by the comparative proteomics
ORGANISM(S): Streptococcus Pneumoniae 23f 
2022-12-18 | PXD038886 |
Our study identify that methionine inhibits N-terminus of GSDME (GSDME-NT) -mediated pyroptosis by dampening its endocytotic degradation. This process is regulated by methionine metabolite spermidine,which can bind with proteins to regulate their biological function. Thus,the binding proteins of sp...
ORGANISM(S): Homo Sapiens 
2025-01-21 | PXD060003 |
Our study identify that methionine inhibits N-terminus of GSDME (GSDME-NT) -mediated pyroptosis by dampening its endocytotic degradation. Thus,the binding proteins of GSDME-NT are detected in the presence or absence of Methionine for futher exploration。
ORGANISM(S): Homo Sapiens 
2025-01-19 | PXD059954 |
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