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TranscriptomicsRotenone susceptibility phenotype in olfactory derived patient cells as a model of idiopathic Parkinson’s disease
Physiologically relevant cellular models are critical for understanding complex pathological processes. Parkinson’s disease (PD) is the second most common neurodegenerative disorder characterised by motor and non-motor symptoms. Several cellular models for PD have been developed to reproduce the a...
ORGANISM(S): Homo sapiens 
2016-10-04 | E-MTAB-4164 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of human olfactory neurosphere-derived cell lines from healthy and idiopathic Parkinsons disease individuals.
The human olfactory epithelium represents a readily accessible source of adult neural cell types which can be propagated in vitro. We have used this feature to establish olfactory neurosphere-derived (hONS) cells lines from patients with idiopathic Parkinson's disease (PD) and healthy controls. We i...
ORGANISM(S): Homo sapiens 
2011-07-14 | E-TABM-879 | biostudies-arrayexpress
ProteomicsImprovements in glycoproteomics through architecture changes to the Orbitrap Tribrid MS platform
Hardware changes introduced on the Orbitrap Ascend MultiOmics Tribrid MS include dual ion routing multipoles (IRMs) that can enable parallelized accumulation, dissociation, and Orbitrap mass analysis of three separate ion populations. The balance between these instrument functions is especially impo...
ORGANISM(S): Homo sapiens (Human) 
2025-09-14 | PXD058153 | Pride
N-glycopeptides Fragmentation Glycoproteomics Tandem mass spectrometry O-glycopeptides Electron transfer dissociation 
TranscriptomicsInfectious hematopoietic necrosis virus (IHNV) persistence in Sockeye Salmon: effect on brain transcriptome and response to the viral mimic poly(I:C)
To characterise the transcriptional response in brain of Sockeye Salmon (Oncorhynchus nerka) that were persistently infected with infectious hematopoietic necrosis virus (IHNV) and to determine whether carrying the IHNV affects the ability to respond to other immunological challenges we compared the...
ORGANISM(S): Oncorhynchus nerka 
2015-08-10 | E-GEOD-65241 | biostudies-arrayexpress
UnknownPerceived Acceptability of Technology Modalities for the Provision of Universal Child and Family Health Nursing Support in the First 6-8 Months After Birth: Cross-Sectional Study.
Not available
S-EPMC11462103 | biostudies-literature
UnknownGene Ontology Causal Activity Modeling (GO-CAM) moves beyond GO annotations to structured descriptions of biological functions and systems.
Not available
S-EPMC7012280 | biostudies-literature
TranscriptomicsExperimental identification of miR-378-3p targets by overexpression and silencing in murine NIH-3T3 fibroblasts
MicroRNAs (miRNAs) are short noncoding RNA molecules regulating the expression of mRNAs. Target identification of miRNAs is computationally difficult due to the relatively low homology between miRNAs and their targets. We provide data here utilizing an experimental approach to identify targets of mm...
ORGANISM(S): Mus musculus 
2012-08-07 | E-GEOD-34873 | biostudies-arrayexpress
UnknownAssociation of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case-control study.
Not available
S-EPMC3208320 | biostudies-literature
UnknownAsthma and landscape fire smoke: A Thoracic Society of Australia and New Zealand position statement.
Not available
S-EPMC10946536 | biostudies-literature
UnknownFatigue in levodopa-naive subjects with Parkinson disease.
Not available
S-EPMC2937041 | biostudies-literature
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