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ProteomicsPeptidomics analysis of dromedary camel supraoptic nucleus by tandem mass spectrometry
Peptides were qualitatively characterized in supraoptic nuclei (SON)of dromedary camels by liquid chromatography-mass spectrometry/mass spectrometry. Samples collected in winter and summer were analyzed separately. Qualitative seasonal differences were noted. The presence of the PMCH hormone by dete...
ORGANISM(S): Camelus dromedarius (Dromedary) (Arabian camel) 
2019-11-11 | PXD013869 | Pride
Peptidomics Dehydration Supraoptic nucleus (son) 
ProteomicsUnveiling Dopamine and Met-Enkephalin Dynamics: Simultaneous Co-Detection in Rat Striatum
Project description Fast -scan cyclic voltammetry was coupled with carbon microelectrodes for co-detection of dopamine and met-enkephalin at single recording sites in rat striatal slices. The measurements used a specifically designed voltammetric waveform to minimize sensitivity to dopamine, maximiz...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-12-22 | PXD067765 | Pride
Proenkephalin Mass spectrometry Solid-phase extraction Opioid peptide Carbon-fiber microelectrode Fast-scan cyclic voltammetry Mesolimbic pathway 
ProteomicsNeuropeptides in the Extracellular Space of the Mouse Cortex Measured by In Vivo Nanodialysis Probe
Neuropeptides are key neuromodulators in the central nervous system that shape sensory processing, yet their extracellular dynamics in the somatosensory cortex (S1) remain poorly understood. This study applies an innovative membrane-free silicon nanodialysis (ND) probe coupled with liquid chromatogr...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD066497 | Pride
Prm-pasef In vivo sampling Neuropeptides Dda‑pasef 
ProteomicsProfiling Neuropeptides in Adrenomedullary Chromaffin Cells: Insights into Regulated Release via Electrical and Chemical Stimulation
Despite longstanding recognition that the adrenal medulla is a major source of catecholamines and opioid peptides, the dynamic co-release of these signaling molecules—and the full complexity of their molecular forms—remains poorly understood. This study addresses this gap by integrating real-time el...
ORGANISM(S): Bos taurus (Bovine) 
2026-06-29 | PXD067807 | Pride
Cyclic voltammetry Proenkephalin Trapped ion mobility spectrometry Neuropeptides release Bovine adrenal slices 
ProteomicsPACAP and other neuropeptide targets link chronic migraine and opioid-induced hyperalgesia in mouse models
Understanding the precise molecular mechanisms behind chronic pain disorders such as migraine and opioid induced hyperalgesia (OIH) has been a long-standing goal met with limited success. Neuropeptides, which play a vital role in several physiological processes are also hypothesized to be involved i...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-06 | PXD013362 | Pride
Peptidomics Lc-ms Label-free 
ProteomicsSingle Cell Proteoform Analysis Using scPiMS
We introduce single-cell Proteoform imaging Mass Spectrometry (scPiMS), which realizes the benefit of direct solvent extraction and MS detection of intact proteins from single cells drop casted onto glass slides. Sampling and detection of whole proteoforms by individual ion mass spectrometry enables...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-02-02 | MSV000093994 | MassIVE
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